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102-61-4 Usage

Enzyme inhibitor

This trans-stilbene derivative (FW = 212.25 g/mol; CAS 102-61-4; M.P. = 155.5-156°C; low solubility in water), also known as (E) -3,5-stilbenediol and trans-3,5-dihydroxystilbene and named systematically as 5-[ (E) -2- phenylethenyl]benzene-1,3-diol, occurs naturally in the hardwood of pine and other woody plants. Pinosylvin exxhibits micromolar Ki values for specific isozymes of stilbene synthase and chalcone synthase. Target (s) : chalcone synthase; stilbene synthase; tyrosinase, or monophenol monooxygenase.

Check Digit Verification of cas no

The CAS Registry Mumber 102-61-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 102-61:
(5*1)+(4*0)+(3*2)+(2*6)+(1*1)=24
24 % 10 = 4
So 102-61-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H14O2/c16-14-9-13(10-15(17)11-14)8-4-7-12-5-2-1-3-6-12/h1-7,9-11,16-17H,8H2/b7-4+

102-61-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name trans-pinosylvin

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:102-61-4 SDS

102-61-4Downstream Products

102-61-4Related news

pinosylvin (cas 102-61-4) reduced migration and invasion of oral cancer carcinoma by regulating matrix metalloproteinase-2 expression and extracellular signal-regulated kinase pathway08/03/2019

BackgroundPinosylvin possesses several biological properties, including anti-inflammatory, antitumor, and antioxidant characteristics. However, the effects of pinosylvin on the migration and invasion of human oral cancer cells and the underlying mechanisms remain unclear.detailed

102-61-4Relevant articles and documents

PH-switched HRP-catalyzed dimerization of resveratrol: A selective biomimetic synthesis

Li, Chang,Lu, Jing,Xu, Xiaofei,Hu, Ruilin,Pan, Yuanjiang

, p. 3281 - 3284 (2012)

A selective, concise and green biomimetic synthesis strategy of seven resveratrol dimers from natural resveratrol monomer as starting material is described. By succinct adjustment of environmental pH, the enzyme used, horseradish peroxidase (HRP), can perform in three distinctly different patterns and five dimers form with considerable selectivity. Two other derivative dimers are subsequently synthesized.

Harris,Carney

, p. 2053 (1966)

TRPA1 channels as targets for resveratrol and related stilbenoids

Nalli, Marianna,Ortar, Giorgio,Moriello, Aniello Schiano,Morera, Enrico,Di Marzo, Vincenzo,De Petrocellis, Luciano

, p. 899 - 902 (2016/05/24)

A series of twenty resveratrol analogues was synthesized and tested on TRPA1 and TRPV1 channels. None was able to significantly modulate TRPV1 channels. Conversely, most of them exhibited remarkably higher TRPA1 modulating activity than resveratrol. Optimal potency was observed with ortho monoxygenated stilbenes 6 and 17.

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