10202-46-7Relevant academic research and scientific papers
Triazine derivative, preparation method and application thereof
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Paragraph 0057-0064, (2021/05/12)
The invention belongs to the technical field of organic electroluminescent material electron transport layers, and particularly relates to a triazine derivative, a preparation method and application thereof, wherein the structure of the triazine derivative is shown as a general formula (I). The triazine derivative with the structure as shown in the general formula (I) has better transmission capacity as an electron transmission material of the organic electroluminescent device, wherein the efficiency of the organic electroluminescent device can be remarkably improved, and the working voltage of the organic electroluminescent device is reduced.
Synthesis method of 2, 4-dihalogen-6-aryl substituted triazine derivative
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Paragraph 0072; 0076; 0080-0081, (2021/02/10)
The invention belongs to the technical field of compound synthesis, and particularly discloses a synthesis method of a 2, 4-dihalogen-6-aryl substituted triazine derivative. The synthesis method comprises the following steps: generating an intermediate triazine diketone compound from an aryl formate compound and biuret under the action of alkali, and reacting under the action of a halogenating reagent to obtain the 2, 4-dihalogen-6-aryl substituted triazine derivative. The method has the characteristics of cheap and accessible raw materials, can greatly lower the production cost, has the advantages of mild reaction conditions, single reaction product, fewer byproducts and no impurity removal difficulty, is simple in technological operation, can easily obtain the high-purity product, and issuitable for large-scale industrial production.
Luminescent material and application thereof
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Paragraph 0073-0076; 0087-0090, (2020/06/20)
The invention discloses a novel organic compound. The novel organic compound has a structure represented by formula (1), wherein Ar1 and Ar2 are independently selected from one of C1-C12 alkyl, C1-C12alkoxy, halogen, cyano, nitro, hydroxyl, silyl, amino, substituted or unsubstituted C6-C30 arylamino, substituted or unsubstituted C3-C30 heteroarylamino, substituted or unsubstituted C6-C30 aryl andsubstituted or unsubstituted C3-C30 heteroaryl; L1 to L4 are each independently selected from one of a single bond, a substituted or unsubstituted C6-C30 arylene group, and a substituted or unsubstituted C3-C30 heteroarylene group; and Hy is represented by formula (Hy1)or (Hy2). The compound disclosed by the invention is suitable for being used as a luminescent material in an OLED device, and canshow excellent device performance and stability. The invention also discloses an organic light-emitting device adopting the compound with the general formula.
Method for synthesizing triazine compound by Friedel-Crafts reaction micro-channel method
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Paragraph 0014-0016; 0020, (2020/05/02)
The invention discloses a method for synthesizing a triazine compound by a Friedel-Crafts reaction micro-channel method. The method comprises the following steps: carrying out mixing dissolving on cyanuric chloride represented by a formula (I), a compound represented by a formula (II), a Lewis acid as a catalyst and an organic solvent to obtain a reaction solution for later use; replacing and exhausting the air in a micro-channel reactor by using nitrogen, injecting the prepared reaction liquid into the micro-channel reactor through a metering pump, carrying out a Friedel-Crafts reaction, controlling the reaction temperature to be 0-120 DEG C, controlling the reaction retention time to be 10-180 minutes, and carrying out post-treatment on the reaction liquid flowing out of the micro-channel reactor to obtain the triazine compound represented by a formula (III), wherein in the formula (II) and the formula (III), the substituent R1 is hydrogen, methyl, hydroxyl, methoxy or chlorine atom,and the substituent R2 is hydrogen, methyl or hydroxyl. By adopting the micro-channel reactor, the corresponding reaction conditions are optimized, the mass transfer and heat transfer effects of thereaction are good, the reaction time is shortened, side reactions are reduced, and the yield of the target product is high.
The triazine compound and its manufacturing method (by machine translation)
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Paragraph 0095; 0096, (2017/11/03)
Synthesis of charge transport materials used [to] 4, 6 - dichlorotriazine compounds useful as intermediates in organic electroluminescent compound. The general formula (1b) [solution]4, 6 - dichlorotriazine compounds as shown. [Drawing] no (by machine translation)
A Sequential Suzuki Coupling Approach to Unsymmetrical Aryl s-Triazines from Cyanuric Chloride
Wang, Chen,Zhang, Jiehui,Tang, Jie,Zou, Gang
supporting information, p. 2514 - 2519 (2017/07/22)
A practical approach has been developed for efficient synthesis of unsymmetrical aryl s-triazines via highly selective sequential Suzuki coupling of cyanuric chloride (2,4,6-trichlorotriazine) with aryl or vinyl boronic or diarylborinic acids catalysed by 0.1–0.5 mol% Pd(PPh3)2Cl2 under mild conditions. The second and third Suzuki couplings for unsymmetrically trisubstituted aryl s-triazines could be more practically conducted in one-pot procedure. An electron-withdrawing conjugate group at phenyl ring of arylboronic acids was unexpectedly found to completely block the coupling while steric hindrance from an ortho electron-donating substituent could be overcome. (Figure presented.).
Combinatorial solid-phase synthesis of 4,6-diaryl and 4-aryl, 6-alkyl-1,3,5-triazines and their application to efficient biofuel production
Kim, Jaoon Y. H.,Lee, Jae Wook,Lee, Woo Sirl,Ha, Hyung-Ho,Vendrell, Marc,Bork, Jacqueline T.,Lee, Youngsook,Chang, Young-Tae
scheme or table, p. 395 - 398 (2012/09/05)
Herein we report the solid-phase synthesis of a combinatorial aryl, alkyl-triazine library and its application to biofuel production. The combination of Grignard reactions and solid supported Suzuki coupling reactions afforded unique 120 triazine compounds with high purities and minimum purification steps. Through an unbiased phenotypic screening for improved biofuel generation in oleaginous yeast, we found one diaryl triazine derivative (E4) which increased the biolipid production up to 86%.
Novel orthogonal synthesis of a tagged combinatorial triazine library via grignard reaction
Lee, Jae Wook,Bork, Jacqueline T.,Ha, Hyung-Ho,Samanta, Animesh,Chang, Young-Tae
experimental part, p. 1000 - 1006 (2010/03/01)
To expand the diversity of 1,3,5-triazine libraries to aryl and alkyl functionalities through the CC bond, we employed a novel orthogonal synthesis via Grignard monoalkylation or monoarylation of cyanuric chloride in solution to prepare aryl- or alkyl-substituted triazine building blocks. These aryl- or alkyl-substituted triazine building blocks were captured by a resin-bound amine, followed by amination and acidic cleavage with high purity. Herein, we demonstrate a novel orthogonal synthesis of a tagged aryl- and alkyl-triazine library on solid support, utilizing building blocks prepared via Grignard reaction in solution. Through incorporation of a triethylene glycol linker at one of the alternate sites on the triazine scaffold we explored an intrinsic tagged library approach. CSIRO 2009.
Synthesis and biological evaluation of novel 1,3,5-triazine derivatives as antimicrobial agents
Zhou, Chunhui,Min, Jaeki,Liu, Zhigang,Young, Anne,Deshazer, Heather,Gao, Tian,Chang, Young-Tae,Kallenbach, Neville R.
, p. 1308 - 1311 (2008/09/19)
Numerous studies have contributed to the development of natural and synthetic antimicrobial peptides as a prospective source of antibiotic agents. Based on the concept that cationic charge, bulk, and lipophilicity are major factors determining antibacterial activity in these peptides, we designed and screened several combinatorial libraries based on 1,3,5-triazine as a template. A set of compounds were identified to show potent antimicrobial activity together with low hemolytic activity.
S-TRIAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME
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Page/Page column 36, (2009/01/20)
Novel s-triazine compounds are disclosed and represented by the following: formula (Ia). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, where microbial infection is either a direct cause or a related condition.
