102162-49-2

Upstream product

• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 170895-01-9 1-(3-phenylpropoxycarbonyl)-1H-imidazole 
• 124-38-9 carbon dioxide 
• 637-59-2 1-Bromo-3-phenylpropane 
• 4119-41-9 1-iodo-3-phenylpropan 
• 584-08-7 potassium carbonate 
• 69804-99-5 3-phenylpropanol methanesulfonate 
• 104-52-9 phenylpropyl chloride 
• 122-97-4 3-Phenyl-1-propanol 
• 530-62-1 1,1'-carbonyldiimidazole 
• 534-17-8 caesium carbonate 
• 3742-75-4 3-phenylpropyl 4-methylbenzenesulfonate 
• 503-38-8 trichloromethyl chloroformate 
• 6324-79-4 ethyl (3-phenylpropyl) carbonate 

Downstream Products

• 220579-78-2 <3-<4'-(methyl)-2-oxoacetyl>phenyl>propylcarbonate 
• 220579-83-9 <4-(3-<<6-(6-aminopurin-9-yl)-2,2-dimethyltetrahydrofuro<3,4-d><1,3>dioxol-4-ylmethyl>-amino>-propyl)-phenyl>-oxoacetic acid methyl ester 
• 220579-79-3 methyl <4-(3-hydroxypropyl)>-α-oxobenzeneacetate 
• 220579-80-6 methyl <4-(3-bromopropyl)>-α-oxobenzeneacetate 

Relevant academic research and scientific papers

Mechanistic insights into Br?nsted acid-induced nucleophilic substitution of aliphatic imidazole carbamate with halide ions

Herein we report interesting reactivity of imidazole carbamate towards nucleophilic substitution with halide ions under Br?nsted acidic conditions. Depending upon reaction conditions, halide ions could readily attack the carboxyl position and trigger decarboxylative alkyl halide formation. Alternatively, halide ions were also found to competitively undergo nucleophilic acyl substitution, which ultimately results in the generation of carbonate dimerization product.

Method for synthesis of organic carbonates

In the present invention, provided is a method for synthesizing organic carbonates, comprising the steps of providing a mixture solution of ionic liquid and alcohol activating reagent; introducing carbon dioxide sources with acidity and alkalinity to the mixture solution; and making the alcohol react with the carbon dioxide source and accordingly obtaining products through the binding of the alcohol and the carbon dioxide source.COPYRIGHT KIPO 2015

Metal-free synthesis of cyclic and acyclic carbonates from CO2 and alcohols

Diverse cyclic and acyclic carbonates such as ethylene carbonate, propylene carbonate, glycerol carbonate, and dimethyl carbonate were synthesized in moderate to good yields by the direct coupling of the corresponding alcohols with carbon dioxide in the absence of metal catalysts and inorganic bases. The direct carbonation mechanism of alcohols in the presence of 1,8-diazabicyclo[5. 4.0]undec-7-ene, 1-butyl-3-methylimidazolium hexafluorophosphate, and dibromomethane was probed by 18O-labeling experiments and chiral alcohol experiments.

Metal-Free Synthesis of Cyclic and Acyclic Carbonates from CO2 and Alcohols

Diverse cyclic and acyclic carbonates such as ethylene carbonate, propylene carbonate, glycerol carbonate, and dimethyl carbonate were synthesized in moderate to good yields by the direct coupling of the corresponding alcohols with carbon dioxide in the absence of metal catalysts and inorganic bases. The direct carbonation mechanism of alcohols in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene, 1-butyl-3-methylimidazolium hexafluorophosphate, and dibromomethane was probed by 18O-labeling experiments and chiral alcohol experiments. Diverse cyclic and acyclic carbonates were synthesized in moderate to good yields by the direct coupling of alcohols with carbon dioxide in the absence of metal catalysts and inorganic bases. The direct carbonation mechanism of alcohols in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) was probed by an 18O-labeling experiment and a chiral alcohol experiment.

Synthesis of symmetrical organic carbonates via significantly enhanced alkylation of metal carbonates with alkyl halides/sulfonates in ionic liquid

We report a new phosgene-free method for the synthesis of symmetrical organic carbonates via alkylation of metal carbonate with various alkyl halides and sulfonates in 1-n-butyl-3-methyl-imidazolium hexafluorophosphate, [bmim] [PF6], as an ecofriendly reaction media. Alkylation of metal carbonate in various ionic liquids with 1-bromo-3-phenylpropane (1a) as a model reactant has thoroughly been investigated. Potassium and cesium carbonates appeared to be the most suitable metal carbonate due to their high solubility in ionic liquids. Besides good to excellent yields, this simple and convenient methodology is devoid of highly toxic and harmful chemicals such as phosgene and carbon monoxide, which is an additional advantage.

Solubilizing agents/solvents for organic UV filters

The invention relates to the use of compounds of the general formula (I) wherein R,R′═HC1-5-hydrocarbon radical, —O—C1-5-oxyhydrcarbon radical and are identical or different R1, R2, R3═H, C1-5-hydrocarbon radical and are identical or different, X,Y═—O—; —O—C(O)—; —(O)C—O— and are identical or different, A=Aα=—O—C(O)—O—; Aβ=R4—CH2C(CH2—)3, Aγ=—C(H)isopropyl, R4═R4δ=—CH3; R4ε=—[CH2—CH(R1)]e-(Y)d—(CH2)c-Ph(R)a, a,b=1 to 5 and are identical or different, c,k=0 to 5 and are identical or different, d,h=0 or 1 and are identical or different, e,g=0 or 1 and are identical or different, f=0 or 1, m=1 to 3, n=0 or 1, as solubilizing agents/solvents for dissolving organic UV filters.

Method for producing symmetrical and asymmetrical carbonates

Process for the preparation of symmetrical and asymmetrical carbonates of the general formula I by reaction of alcohols of the general formula II and alkyl or aryl halides of the general formula III,R—OH??IIR′—HAL??IIIwith carbon dioxide and caesium carbonate at room temperature in dipolar aprotic solvents.

A useful conversion of alcohols to alkyl fluorides

A useful conversion of alcohols to alkyl fluorides via their fluoroformates is introduced. The fluoroformates are obtained in nearly quantitative yield from the alcohols by treatment with COF2 (generated in situ from bis(trichloromethyl) carbonate) in ether with KF as an added acid scavenger. The neat fluoroformates are cleaved to the fluorides by heating at 120-125°C using hexabutylguanidinium fluoride (HBGF) as the catalyst.

A safe synthesis of symmetrical carbonates from alkyl halides and tetraethylammonium carbonate

A safe and mild procedure for the synthesis of organic carbonates from alkyl halides and tetraethylammonium carbonate (TEAC) is described. This method avoids the use of classical toxic and harmful chemicals like phosgene and carbon monoxide and works unde