10220-98-1

Upstream product

• 121-68-6 dithiobenzoic acid 
• 52185-81-6 N-chlorocyclohexanamine 
• 1122-82-3 isothiocyanatocyclohexane 
• 98-87-3 benzylidene dichloride 
• 108-91-8 cyclohexylamine 
• 611-73-4 Benzoylformic acid 
• 101960-58-1 [(Z)-Cyclohexylimino]-phenyl-acetic acid 
• 690634-04-9 benzotriazole-1-carbothioic acid cyclohexylamide 
• 1759-68-8 N-benzoylcyclohexylamine 
• 35124-71-1 S-(Thiobenzoyl)-hydrosulfamin 
• 98-07-7 Benzotrichlorid 
• 100-52-7 benzaldehyde 
• 110-91-8 morpholine 
• 141-84-4 2-thioxo-4-thiazolidinone 

Downstream Products

• 83927-22-4 N-Cyclohexyl-thiobenzimidic acid phenyl ester 
• 882-33-7 diphenyldisulfane 
• 1759-68-8 N-benzoylcyclohexylamine 
• 113327-03-0 C₂₆H₃₁N₃O₆S 
• 113327-04-1 C₂₇H₃₃N₃O₆S 
• 113327-11-0 1-((2R,5S)-3-Cyclohexyl-2-ethoxy-4-oxo-2,5-diphenyl-thiazolidin-5-yl)-4-phenyl-[1,2,4]triazolidine-3,5-dione 
• 100616-90-8 1-cyclohexyl-5-phenyl-1H-tetrazole 
• 113326-84-4 3-cyclohexyl-2,5-diphenylthiazolium-4-olate 

Relevant academic research and scientific papers

Sulfonic acid functionalized nano Γ-Al 2O 3: A new, efficient, and reusable catalyst for synthesis of thioamides

Sulfonic acid functionalized nano γ-Al2O3 is easily prepared by the reaction of nano γ-Al2O3 with 1,3-propane sulfone. This reagent can be used as an eficient catalyst for the synthesis of thioamides. This new method consistently has the advantages of excellent yields and short reaction times. Further, the catalyst can be recovered for several times.

Microwave-Assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines: A rapid and efficient protocol for thioamides

An efficient protocol for synthesis of thioamides was developed via the microwave-Assisted iodine-catalyzed oxidative coupling of dibenzyl(difurfuryl)disulfides with amines. This process is scalable and tolerates a wide spectrum of amines to deliver the corresponding products in moderate to excellent yields in 10 minutes, providing a cheap and rapid approach to thioamides.

Sulfur-Catalyzed Oxidative Coupling of Dibenzyl Disulfides with Amines: Access to Thioamides and Aza Heterocycles

In the presence of catalytic amounts of elemental sulfur, dibenzyl disulfide/DMSO was found to be an excellent thiobenzoylating agent of amines to provide a wide range of thioamides. The reaction becomes autocatalytic when anilines substituted by an o-cyclizable group were used as nucleophile, leading to the corresponding 2-aryl aza heterocycles. (Figure presented.).

Iodine-Promoted Synthesis of Thioamides from 1,2-Dibenzylsulfane and Difurfuryl Disulfide

Thioamides can be generated at 100 °C in high yield through the reaction of 1,2-dibenzyldisulfane with difurfuryldisulfide using iodine as oxidant and DMSO as solvent. The protocol is metal- and additive-free, providing a convenient and economical way for the synthesis of various kinds of thioamides under mild conditions.

Direct conversion of methylarenes into dithiocarbamates, thioamides and benzyl esters

A new strategy for the synthesis of a variety of dithiocarbamates and thioamides has been developed employing inexpensive and readily available methylarenes under metal-free and solvent-free conditions. The approach offers a one-pot procedure and has also been extended to the synthesis of a diverse range of benzyl esters.

Decarboxylative thioamidation of arylacetic and cinnamic acids: A new approach to thioamides

A new decarboxylative strategy has been developed for the synthesis of thioamides via a three-component reaction involving arylacetic or cinnamic acids, amines and elemental sulfur powder, without the need of a transition metal and an external oxidant.

Nano n -propylsulfonated magnetic γ-Fe2O3 as an efficient and reusable catalyst for the synthesis of thioamides

One-pot three-component reactions of aldehydes, amines, and sulfur are carried out in the presence of nano n-propylsulfonated magnetic γ-Fe2O3 as a catalyst for the synthesis of biologically interesting thioamide derivatives. The value of this catalytic method lies in its mild reaction catalyst and conditions, good yields, and ease of handling.

A new application of rhodanine as a green sulfur transferring agent for a clean functional group interconversion of amide to thioamide using reusable MCM-41 mesoporous silica

A novel thionation protocol for amide compounds, with the system rhodanine/secondary amine has been discovered. Clean and efficient synthesis of a variety of thioamides can be achieved through this simple and convenient method using MCM-41 mesoporous silica as an acid catalyst. For this purpose we have synthesized MCM-41 silica and characterized by using an array of sophisticated analytical techniques like BET, HR TEM, EDX, XRD, 29Si MAS NMR and FTIR. This reaction is therefore a very neat example of a functional group interconversion.

Sulfated tungstate: An efficient catalyst for synthesis of thioamides via Kindler reaction

New application of sulfated tungstate, a mildly acidic solid inorganic acid, as reusable heterogeneous catalyst for efficient Kindler reaction, a three component reactions of aldehydes, amines and sulfur, for synthesis of thioamides is discussed.

Ammonium phosphorodithioate: A mild, easily handled, efficient, and air-stable reagent for the conversion of amides into thioamides

A simple, efficient, and new method has been developed for the synthesis of thioamides from amides. As described below, the reaction of a variety of aromatic and aliphatic amides in the presence of ammonium phosphorodithioate as an efficient reagent proceeded effectively to afford the corresponding thioamides in high yields. This method is easy, rapid, and high-yielding for the synthesis of thioamides from amides using an easily handled reagent. Georg Thieme Verlag Stuttgart · New York.