10299-69-1

Usage

Uses

1H-Pyrrolo[2,3-b]pyridine, 2,3-dimethylis used as a chemical intermediate in the synthesis of various organic compounds due to its unique structural properties.
Used in Chemical Synthesis Industry:
1H-Pyrrolo[2,3-b]pyridine, 2,3-dimethylis used as a building block for the synthesis of complex organic molecules, taking advantage of its pyrrole and pyridine rings to form diverse chemical structures.
Used in Research and Development:
1H-Pyrrolo[2,3-b]pyridine, 2,3-dimethylis utilized in research settings to explore its chemical reactivity, potential applications, and to understand its behavior in various chemical reactions.

InChI:InChI=1/C9H10N2/c1-6-7(2)11-9-8(6)4-3-5-10-9/h3-5H,1-2H3,(H,10,11)

Upstream product

• 149489-03-2 tert-butyl (3-ethylpyridin-2-yl)carbamate 
• 49609-84-9 2-Chloronicotinoyl chloride 
• 111108-72-6 (2-chloro-3-pyridinyl)methyl bromide 
• 42330-59-6 (2-chloropyrid-3-yl)methanol 
• 2942-59-8 2-chloronicotinic acid 
• 4930-98-7 pyrid-2-ylhydrazine 
• 78-93-3 butanone 
• 138343-75-6 tert-butyl (3-methylpyridin-2-yl)carbamate 
• 1603-40-3 3-methylpyridin-2-ylamine 

Downstream Products

• 784110-57-2 2,3-Dimethyl-7-(p-fluorophenacyl)pyrrolo[2,3.-b ]pyridine 
• 145934-22-1 2,3-Dimethyl-7-(o-carboxyphenethyl)pyrrolo[2,3-b]pyridine 
• 145933-93-3 2,3-Dimethyl-7(2-trifluoromethylphenacyl)-pyrrolo[2,3-b]pyridine hydrobromide 
• 145958-93-6 2,3-Dimethyl-7-(p-bromophenacyl)pyrrolo[2,3-b]pyridine, hydrobromide 
• 751452-00-3 2,3Dimethyl-7-(p-cyanophenacyl)pyrrolo[2,3-b]pyridine 
• 114570-21-7 1-(2,3-Dimethyl-pyrrolo[2,3-b]pyridin-1-yl)-2-hydroxy-2,2-diphenyl-ethanone 

Relevant academic research and scientific papers

Oxidative cleavage reaction of substituted indoles catalyzed by plant cell cultures

We have developed a novel method for the oxidative cleavage of indole carbon double bonds in the presence of H2O2 using plant cell cultures as peroxidase. The oxidative method has some advantage, as features such as mild reactions, good yields, easy work-up and safety.

Iron-Catalyzed Radical Activation Mechanism for Denitrogenative Rearrangement Over C(sp3)–H Amination

An iron-catalyzed denitrogenative rearrangement of 1,2,3,4-tetrazole is developed over the competitive C(sp3)–H amination. This catalytic rearrangement reaction follows an unprecedented metalloradical activation mechanism. Employing the developed method, a wide number of complex-N-heterocyclic product classes have been accessed. The synthetic utility of this radical activation method is showcased with the short synthesis of a bioactive molecule. Collectively, this discovery underlines the progress of radical activation strategy that should find wide application in the perspective of medicinal chemistry, drug discovery and natural product synthesis research.

A convenient method for the preparation of 5-, 6- and 7-azaindoles and their derivatives

The directed ortho lithiation of 2-tert-butoxycarbonylamino-3-methylpyridine (6a) has provided a convenient method for the preparation of 1H-pyrrolo[2,3-b]pyridine (4a, 7-azaindole). This procedure has been used to prepare a range of 3-substituted 2-tert-butoxycarbonylaminopyridines 6, 2- and 3-substituted and 2,3-disubstituted 1H-pyrrolo[2,3-b]pyridines 4 and shown to be of value in the preparation of 1H-pyrrolo[3,2-c]pyridine (15, 5-azaindole) and 1H-pyrrolo[2,3-c]pyridine (18, 6-azaindole) and derivatives.