103421-77-8

Basic information

• Product Name: R,S-N,N`-bis(α-methylbenzyl)ethylenediamine
• Synonyms: R,S-N,N`-bis(α-methylbenzyl)ethylenediamine
• CAS NO: 103421-77-8
• Molecular Weight: 268.402
• Mol File: 103421-77-8.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: R,S-N,N`-bis(α-methylbenzyl)ethylenediamine(CAS DataBase Reference)
• NIST Chemistry Reference: R,S-N,N`-bis(α-methylbenzyl)ethylenediamine(103421-77-8)
• EPA Substance Registry System: R,S-N,N`-bis(α-methylbenzyl)ethylenediamine(103421-77-8)

Safety Data

• Hazardous Substances Data: 103421-77-8(Hazardous Substances Data)

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 138812-17-6 N,N'-bis<(S)-1-phenylethyl>ethanediimine 
• 106-93-4 ethylene dibromide 
• 107-06-2 1,2-dichloro-ethane 
• 16888-80-5 bis(acetophenone)ethylenediamine 
• 98-84-0 D(+)-α-methylbenzylamine 
• 98-86-2 acetophenone 
• 107-15-3 ethylenediamine 

Downstream Products

• 221232-26-4 Zn((C₂H₅)2CHCO₂)2[(S,S)-N,N'-ethylenebis(1-phenylethylamine)] 
• 235433-17-7 Zn(C₂H₅)2[(S,S)-N,N'-ethylenebis(1-phenylethylamine)] 
• 235422-40-9 (Zn(C₂H₅)(C₆H₅CH(CH₃)NC₂H₄NCH(CH₃)C₆H₅C(CH₃)C₆H₅O))2 
• 235433-16-6 Zn(CH₃)2[(S,S)-N,N'-ethylenebis(1-phenylethylamine)] 
• 235422-39-6 (Zn(C₂H₅)(C₆H₅CH(CH₃)NC₂H₄NCH(CH₃)C₆H₅CHC₆H₅O))2 
• 76695-20-0 3-Ethyl-1,5-bis-(1-phenyl-ethyl)-[1,5,3]diazaphosphepane 
• 76695-25-5 N,N'-Bis-{[(4-chloro-phenyl)-phenyl-phosphanyl]-methyl}-N,N'-bis-(1-phenyl-ethyl)-ethane-1,2-diamine 
• 76695-24-4 N,N'-Bis-{[(4-fluoro-phenyl)-phenyl-phosphanyl]-methyl}-N,N'-bis-(1-phenyl-ethyl)-ethane-1,2-diamine 
• 76695-23-3 N,N'-Bis-[(diphenylphosphanyl)-methyl]-N,N'-bis-(1-phenyl-ethyl)-ethane-1,2-diamine 
• 76695-18-6 3-Phenyl-1,5-bis-(1-phenyl-ethyl)-[1,5,3]diazaphosphepane 
• 76706-77-9 3-Methyl-1,5-bis-(1-phenyl-ethyl)-[1,5,3]diazaphosphepane 
• 94682-34-5 1,4-bis-(1-phenyl-ethyl)-piperazine 
• 171514-21-9 1,3-bis((S)-1-phenylethyl)-1,3,2-diazaphospholidine 2-oxide 

Relevant articles and documents

Enantioselective catalytic rearrangement of cyclohexene oxide with new homochiral bis-lithium amide bases

Cyclohexene oxide can be rearranged with good levels of induction (up to 68% ee) with substoichiometric amounts of chiral bases derived from readily available diamines. The influence of the steric bulk of the amine substituents on the rearrangement enantioselectivity has also been studied.

Imidazolinium chloride salts bearing wingtip groups: Synthesis, molecular docking and metabolic enzymes inhibition

A series of symmetrical imidazolinium chloride salts bearing secondary N-alkyl substituents were synthesized in good yield by the reaction of N,N′-dialkylethane-1,2-diamines and HC(OEt)3 in the presence of NH4Cl. These salts were characterized by spectroscopic methods. All compounds were tested as enzyme inhibitory agents. These novel symmetrical imidazolinium chloride salts derivatives (3a-h) effectively inhibited the cytosolic hCA I and hCA II, BChE, α-glycosidase and AChE with Ki values in the range of 18.41–121.73 nM for hCA I, 12.50–63.12 nM for hCA II, 3.72–34.58 nM for AChE, 5.50–32.36 nM for BChE, and 94.72–364.51 nM for α-glycosidase, respectively. CA isoenzymes play a crucial roles including acid-base balance homeostasis by excreting and secreting protons (H+) due to the CO2 hydration, HCO3 ? reabsorption mechanisms, and renal NH4 + output. Also, the molecular modeling is an implementation for estimation of the binding proximity of symmetrical imidazolinium chloride salts bearing secondary wingtip groups and their inhibition mechanisms and kinetics in atomic levels at the catalytic domains.

Synthesis, structure, and reaction of chiral 2-azidoimidazolinium salts: (7aS)-3-azido-5,6,7,7a-tetrahydro-2-[(1R)-1-phenylethyl]-1H-pyrrolo[1,2-c]imidazolium hexafluorophosphate and 2-azido-1,3-bis[(S)-1-phenylethyl]imidazolinium hexafluorophosphate

Two chiral 2-azidoimidazolinium salts [(7aS)-3-azido-5,6,7,7a-tetrahydro-2-[(1R)-1-phenylethyl]-1H-pyrrolo[1,2-c]imidazolium hexafluorophosphate (2) and 2-azido-1,3-bis[(S)-1-phenylethyl]imidazolinium hexafluorophosphate (3)] were synthesized, and their structures were determined by X-ray single crystal structural analysis. Migratory amidation reaction of enol silyl ether with 3 proceeded, but good diastereoselectivity was not observed in the reaction.

Catalytic enantioselective Steglich rearrangements using chiral N-heterocyclic carbenes

The evaluation of a range of enantiomerically pure NHCs, prepared in situ from imidazolinium or triazolium salt precatalysts, to promote the catalytic enantioselective Steglich rearrangement of oxazolyl carbonates to their C-carboxyazlactones, is reported. Modest levels of enantioselectivity (up to 66% ee) are observed using oxazolidinone derived NHCs.