103628-15-5Relevant articles and documents
Highly Stereoselective Access to an (E)-Vinyl Bromide from an Aryl Ketone Leads to Short Syntheses of (Z)-Tamoxifen and Important Substituted Derivatives
Potter, Gerard A.,McCague, Raymond
, p. 6184 - 6187 (2007/10/02)
The enol triflate derived from a 1-(4-alkoxyphenyl)-2-phenyl-1-butanone is unstable, fragmenting to a vinyl cation that can be trapped by bromide ion.The E isomer of the vinyl bromide which is formed in preference (20:1) gave, upon palladium-catalyzed cou