10443-61-5

Basic information

• Product Name: 4,5-dihydro-2-undecyl-1H-Imidazole
• Synonyms: 1H-Imidazole,4,5-dihydro-2-undecyl-;4,5-dihydro-2-undecyl-1H-Imidazole;2-Hendecylimidazoline;2-Undecyl-1-imidazoline;2-Undecyl-4,5-dihydro-1H-imidazole
• CAS NO: 10443-61-5
• Molecular Formula: C₁₄H₂₈N₂
• Molecular Weight: 224.39
• Mol File: 10443-61-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 79.8 °C
• Boiling Point: 354.3°Cat760mmHg
• Flash Point: 168.1°C
• Appearance: /
• Density: 0.94
• Vapor Pressure: 6.92E-05mmHg at 25°C
• Refractive Index: 1.503
• PKA: 10.93±0.40(Predicted)
• CAS DataBase Reference: 4,5-dihydro-2-undecyl-1H-Imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dihydro-2-undecyl-1H-Imidazole(10443-61-5)
• EPA Substance Registry System: 4,5-dihydro-2-undecyl-1H-Imidazole(10443-61-5)

Safety Data

• Hazardous Substances Data: 10443-61-5(Hazardous Substances Data)

Usage

General Description

4,5-dihydro-2-undecyl-1H-imidazole is a chemical compound with the molecular formula C16H32N2. It is a synthetic imidazole derivative that is often used as an intermediate in the production of various pharmaceuticals and agrochemicals. 4,5-dihydro-2-undecyl-1H-Imidazole has a long alkyl chain, making it hydrophobic and capable of interacting with lipid membranes, which may make it useful for certain applications in drug delivery or as a surfactant. Additionally, it has been investigated for its potential as an antimicrobial agent, particularly in the control of microbial growth in various industrial and agricultural settings. Despite its potential utility, further research is needed to fully understand the biological activity and potential toxicological effects of 4,5-dihydro-2-undecyl-1H-imidazole.

InChI:InChI=1/C14H28N2/c1-2-3-4-5-6-7-8-9-10-11-14-15-12-13-16-14/h2-13H2,1H3,(H,15,16)

Upstream product

• 143-07-7 lauric acid 
• 333-18-6 1,2-diaminoethane dihydrochloride 
• 6780-13-8 1,2-ethanediamine monohydrate 
• 10138-02-0 N-(2-aminoethyl)dodecanamide 
• 65675-17-4 N-(2-amino-ethyl)-lauramide; hydrochloride 
• 7003-56-7 dodecanamide, N,N'-1,2-ethanediylbis- 
• 112-16-3 n-dodecanoyl chloride 
• 106-33-2 ethyl laurate 
• 107-15-3 ethylenediamine 
• 46843-77-0 2-Undecyl-1,4,5,6-tetrahydro-pyrimidine 
• 81066-70-8 ethyl dodecanedithionate 

Downstream Products

• 112-54-9 Dodecanal 
• 16731-68-3 2-undecyl imidazole 

Relevant articles and documents

Bicyclo-imidazoline laurate, synthesis method therefor and application of bicyclo-imidazoline laurate

The invention discloses bicyclo-imidazoline laurate. The bicyclo-imidazoline laurate has a symmetrical molecular structure, comprises two imidazoline heterocycles and two alkyl long chains of lauric acid, and thus, plenty and dense electronic clouds and good hydrophobicity can be provided. The invention further discloses a bicyclo-imidazoline laurate synthesis method, which is low in raw materialcost and high in reaction yield and can achieve industrial production. The invention further discloses an application of the bicyclo-imidazoline laurate. The electrotransport type cationic bicyclo-imidazoline laurate is obtained through activating bicyclo-imidazoline laurate and is applied to the rusting prevention of reinforced concrete.

Compositions and method comprising heterocyclic compounds containing two heteroatoms as membrane penetration enhancers

A method and compositions for enhancing absorption of topically administered physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or formulation for local or systemic use, comprising a therapeutically effective amount of a pharmaceutically active agent and a non-toxic, effective amount of penetration enhancing agent of the formula I: STR1 wherein R is a saturated or unsaturated, straight or branched, cyclic or acyclic hydrocarbon group with from 1 to 19 carbon atoms, alkoxyalkyl, haloalkyl, specifically trifluoromethyl, alkoxy, amino, alkylamino and acylamino; R' and R" are hydrogen, alkyl, trifluoromethyl, alkoxyalkyl, aminoalkyl, alkyl- and acylaminoalkyl, carboxy, carbalkoxy, hydroxyalkyl or lower alkyl ester thereof; X is O or NR1 wherein R1 is hydrogen, alkyl, alkenyl, alkoxyalkyl, carbalkoxyalkyl, aminoalkyl, alkyl- and acylaminoalkyl, hydroxyalkyl or hydroxyalkyloxyalkyl and lower alkyl ester thereof; and n is 2 or 3 are disclosed.

Rapid Synthesis and Interconversions of Fatty 4,5-Dihydroimidazoles and Fatty 1,4,5,6-Tetrahydropyrimidines. Thermal Cyclizations of Fatty Amides Involving Phenyl Phosphorodiamidate

Brief heating of ethane-1,2- and propane-1,3-bis-fatty amides at 235-250 deg C with phenyl phosphorodiamidate gave routes to high yields of 2-fatty alkyl-4,5-dihydroimidazoles and 1,4,5,6-tetrahydropyrimidines.Ready interconversions of fatty dihydroimidazoles and tetrahydropyrimidines, involving diamine exchange with solvent, were observed on brief heating of these materials in ethylenediamine and trimethylenediamine as solvents.