104600-19-3

Basic information

• Product Name: Propanedioic acid, [2-(methylthio)benzoyl]-, diethyl ester
• CAS NO: 104600-19-3
• Molecular Formula: C15H18O5S
• Molecular Weight: 310.371
• Mol File: 104600-19-3.mol

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [2-(methylthio)benzoyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [2-(methylthio)benzoyl]-, diethyl ester(104600-19-3)
• EPA Substance Registry System: Propanedioic acid, [2-(methylthio)benzoyl]-, diethyl ester(104600-19-3)

Safety Data

• Hazardous Substances Data: 104600-19-3(Hazardous Substances Data)

Upstream product

• 3724-10-5 2-(methylthio)benzoic acid 
• 65-85-0 benzoic acid 
• 1442-03-1 2-methylsulfanyl-benzoyl chloride 
• 105-53-3 diethyl malonate 

Downstream Products

• 1441-97-0 2'-(methylthio)acetophenone 
• 103318-68-9 3-Cyclopropylamino-2-(2-methylthiobenzoyl)acrylsaeure-ethylester 
• 103318-67-8 (Z)-3-Ethoxy-2-(2-methylsulfanyl-benzoyl)-acrylic acid ethyl ester 
• 149739-35-5 3(5)-<2'-methylthiophenyl>pyrazole 
• 103318-66-7 2-Methylthiobenzoylessigsaeure-ethylester 

Relevant articles and documents

Synthesis of pyrazolo[1,5-b][1,2]benzisothiazoles

The synthesis of some pyrazolo[1,5-b] [1,2]benzisothiazoles is described. The route is based on the reaction between 3(5)-[2′-methylthiophenyl]pyrazoles and its derivatives with N-chlorosuccinimide.

Cycloaracylation of Enamines, I. - Synthesis of 4-Quinolone-3-carboxylic Acids

Starting with o-halobenzoyl chlorides 4 and open-chain secondary enamines 5, a new synthesis of 4-quinolone-3-carboxylic acids 12 is described.The reaction of 7-haloquinolone-3-carboxylic acids 12a-k with aliphatic amines 14 produces highly active antibacterial 7-aminoquinolone-3-carboxylic acids 15.The main product of the 1-cyclopropyl series, "ciprofloxacin" (15a), is being developed as a broad-spectrum chemotherapeutic agent.