106565-22-4

Upstream product

• 28918-09-4 2-benzyl-1,3-diphenyl-propane-1,3-dione 
• 100-39-0 benzyl bromide 
• 120-46-7 1,3-diphenylpropanedione 
• 98-86-2 acetophenone 
• 94-41-7 benzalacetophenone 
• 100-52-7 benzaldehyde 
• 4663-33-6 1,3-diphenyl-3-hydroxypropene 

Downstream Products

• 1375090-82-6 2-benzyl-1,3-diphenylpropane-1,3-diol 
• 1375090-85-9 2-benzyl-1,3-diphenylpropane-1,3-diol 
• 1373153-95-7 C₃₈H₄₄N₂O₈ 
• 1373153-99-1 C₃₈H₄₄N₂O₈ 

Relevant academic research and scientific papers

Potassium Base-Promoted Diastereoselective Synthesis of 1,3-Diols from Allylic Alcohols and Aldehydes through a Tandem Allylic-Isomerization/Aldol–Tishchenko Reaction

This study reports the first base-promoted aldol–Tishchenko reactions of allylic alcohols with aldehydes initiated by allylic isomerization. The reaction enables the diastereoselective synthesis of a variety of 1,3-diols with three contiguous stereogenic centers. Unlike commonly reported systems, our method allows the use of readily available allylic alcohols as nucleophiles instead of enolizable aldehydes and ketones.

Application of a novel 1,3-diol with a benzyl backbone as chiral ligand for asymmetric oxidation of sulfides to sulfoxides

A chiral 1,3-diol with a benzyl backbone has been used for the asymmetric oxidation of sulfides to sulfoxides. Moderate to good yields and enantioselectivity (upto 87% ee) have been observed.

Chelation- and Nonchelation-Controlled Reductions of β-Dicarbonyl Compounds to 1,3-Diols with Three Chiral Centers

1,3-Diols 5 with three chiral centers are easily obtained, as a diastereoisomer mixture, by reduction of β-dicarbonyl compounds 4 with lithium aluminum hydrides.The diastereoisomer ratio depends largely on the solvent and the nature of the reducing agent.