106891-32-1

Basic information

• Product Name: METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE
• Synonyms: METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE;N-Methyl-2-(2-thienyl)ethanamine hydrochloride;2-Thiopheneethanamine, N-methyl-;N-Methyl-2-(thiophen-2-yl)ethanamine;methyl-[2-(2-thienyl)ethyl]amine hydrochloride;N-methyl-2-(thiophen-2-yl)ethanamine hydrochloride;N-methyl-2-thiophen-2-ylethanamine hydrochloride;N-methyl-2-thiophen-2-yl-ethanamine hydrochloride
• CAS NO: 106891-32-1
• Molecular Formula: C₇H₁₁NS
• Molecular Weight: 141.23
• Mol File: 106891-32-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE(106891-32-1)
• EPA Substance Registry System: METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE(106891-32-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 106891-32-1(Hazardous Substances Data)

Usage

Uses

N-Methyl-2-thiopheneethanamine is used to prepare DNA-dependent protein.

Upstream product

• 26478-16-0 2-(2-Bromoethyl)thiophene 
• 30433-91-1 [2-(2-thyenyl)ethyl]amine 
• 61380-07-2 2-(thiophen-2-yl)ethyl methanesulfonate 
• 74-89-5 methylamine 
• 95523-36-7 [2]thienyl-acetic acid methylamide 
• 28783-49-5 N-(2-(thien-2-yl)ethyl)formamide 
• 5402-55-1 2-thiophenethanol 

Downstream Products

• 202811-21-0 N-((1R)-2-(biphenyl-4-yl)-1-(N-methyl-N-(2-(2-thienyl)ethyl)carbamoyl)ethyl)-N-methylcarbamic acid tert-butyl ester 
• 202811-02-7 {1-[3-(methyl-{1-[methyl-(2-thiophen-2-yl-ethyl)-carbamoyl]-2-naphthalen-2-yl-ethyl}-carbamoyl)-phenyl]-ethyl}-carbamic acid tert-butyl ester 
• 202811-23-2 (3E)-4-(N-((1R)-2-(biphenyl-4-yl)-1-(N-methyl-N-(2-(thien-2-yl)ethyl)carbamoyl)ethyl)-N-methylcarbamoyl)-1,1-dimethylbut-3-enylcarbamic acid tert-butyl ester 

Relevant articles and documents

Iron-Catalyzed Intramolecular C—H Amidation of N-Benzoyloxyureas

A redox-neutral Fe-catalyzed intramolecular C—H amidation of N-benzoyloxyureas is described. This methodology employs a simple iron complex in situ generated from Fe(OTf)2 and bipyridine as the catalyst and N-benzoyloxyureas as the nitrene prec

Smiles-type free radical rearrangement of aromatic sulfonates and sulfonamides: Syntheses of arylethanols and arylethylamines

Smiles-type free radical rearrangements of arenesulfonates and arenesulfonamides are exploited for synthetic purposes. 4-Substituted benzenesulfonates cause Smiles-type rearrangement only when substituted by an electron withdrawing group. Therefore, ipso-sttack by an alkyl radical on arenesulfonates takes place in an electrophilic manner. Arenesulfonamides rearrange only when the amide nitrogen is substituted by an alkoxycarbonyl group, due to the electron withdrawing nature of this group. Sulfonates and the N-ethoxycarbonylsulfonamide derivatives of naphthalene, quinoline, and thiophene cause more rearrangement and show synthetic utility. Aromatic amino acid analogues were synthesized by Smiles-type rearrangement with moderate yields. The radical Smiles-type rearrangement of sulfonate and sulfonamide derivatives can be a useful synthetic route when we understand the electronic character of these reactions.

Compounds with growth hormone releasing properties

Novel peptide derivatives, compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone are disclosed. The peptides have the formula (I): STR1 wherein a, b, A, R1, L1, D, R3, R4, R2, L2, E and G are as defined in the specification. These peptides exhibit improved resistance to proteolytic degradation, and hence, improved bioavailability.