107027-12-3

Basic information

• Product Name: N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide
• Synonyms: 8-quinolinecarboxamide, N-[2-(dimethylamino)ethyl]-2-phenyl-; N-[2-(Dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide
• CAS NO: 107027-12-3
• Molecular Formula: C₂₀H₂₁N₃O
• Molecular Weight: 319.4002
• Mol File: 107027-12-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 553.6°C at 760 mmHg
• Flash Point: 288.6°C
• Density: 1.144g/cm³
• Vapor Pressure: 2.67E-12mmHg at 25°C
• Refractive Index: 1.619
• PKA: 13.51±0.46(Predicted)
• CAS DataBase Reference: N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide(107027-12-3)
• EPA Substance Registry System: N-[2-(dimethylamino)ethyl]-2-phenylquinoline-8-carboxamide(107027-12-3)

Safety Data

• Hazardous Substances Data: 107027-12-3(Hazardous Substances Data)

Upstream product

• 95-53-4 o-toluidine 
• 117874-60-9 2-[2-Ethoxycarbonyl-1-phenyl-eth-(E)-ylideneamino]-benzoic acid methyl ester 
• 107027-76-9 8-(methoxycarbonyl)-2-phenyl-4(1H)-quinolone 
• 90034-64-3 2-phenyl-4(1H)-quinolone-8-carboxylic acid 
• 134-20-3 2-carbomethoxyaniline 
• 100-52-7 benzaldehyde 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 107027-34-9 2-phenyl-8-methylquinoline-4-carboxylic acid 
• 5353-90-2 8-methyl-2-phenylquinoline 
• 5093-81-2 2-phenylquinoline-8-carboxylic acid 
• 108-00-9 N,N-dimethylethylenediamine 

Relevant articles and documents

Potential antitumor agents. 57. 2-Phenylquinoline-8-carboxamides as 'minimal' DNA-intercalating antitumor agents with in vivo solid tumor activity

A series of phenyl-substituted derivatives of the 'minimal' DNA-intercalating agent N-[2-(dimethylamino)-ethyl]-2-phenylquinoline-8-carboxamide (1) have been synthesized and evaluated for in vivo antitumor activity, in a continuing search for active compo