1083009-44-2

Usage

Uses

Used in Chemical and Biological Research:
2,6-diiodo-4,4-difluoro-1,3,5,7-tetramethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene is utilized as a fluorescent labeling agent for its ability to enhance the visibility of molecular and cellular processes. Its fluorescence properties allow for the tracking and imaging of biological molecules, providing insights into their behavior and interactions within complex systems.
Used in Fluorescent Imaging Techniques:
In the field of fluorescent imaging, 2,6-diiodo-4,4-difluoro-1,3,5,7-tetramethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene serves as a vital component for visualizing and mapping the distribution of specific molecules within biological samples. Its stability and fluorescence make it suitable for long-term imaging studies, contributing to a better understanding of cellular dynamics.
Used in Advanced Materials and Technology Applications:
2,6-diiodo-4,4-difluoro-1,3,5,7-tetramethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene is also employed as a component in the development of advanced materials and technologies. Its versatility and stability contribute to the creation of innovative products with potential applications in various industries, such as sensing, diagnostics, and optoelectronics.

Upstream product

• 625-82-1 2,4-dimethyl-1H-pyrrole 
• 98-88-4 benzoyl chloride 
• 100-52-7 benzaldehyde 
• 52001-12-4 3,3′,5,5′-tetramethyl-6-phenylpyrromethene 
• 7553-56-2 iodine 
• 680222-61-1 3,3',5,5'-tetramethyl-6-phenylpyrromethene 

Downstream Products

• 1083009-45-3 C₆H₅C(C₄N(CH₃)2CCC₆H₄C(C₆H₅)3)2BF₂ 
• 1083009-46-4 2,6-di-(phenylacetylenyl)-1,3,5,7-tetramethyl-8-phenyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 
• 1191265-84-5 2,6-di-((9-ethyl-9H-carbazol-3-yl)ethynyl)-1,3,5,7-tetramethyl-8-phenyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 
• 1191265-85-6 2,6-di-(4-(N,N-diphenylamino)phenylacetylenyl)-1,3,5,7-tetramethyl-8-phenyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 
• 1329012-14-7 C₃₇H₃₃BF₂IN₃ 
• 1329012-12-5 C₂₈H₂₆BF₂I₂N₃ 
• 1329012-13-6 C₂₄H₂₆BF₂IN₂Si 
• 1350465-89-2 (C₆H₅)C((C₄N(CH₃)2)CC(C₆H₄)C(C₄HN(CH₃)2)2BF₂)2BF₂ 
• 1098053-27-0 4,4-difluoro-8-phenyl-2,6-diethynyl-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene 
• 1350465-90-5 TSi-BDP 
• 1359876-91-7 C₂₇H₂₃BF₂N₂S₂ 
• 1401461-29-7 C₅₅H₄₉BF₂N₄ 
• 1401521-00-3 C₃₈H₃₃BF₂IN₃O 
• 1421071-27-3 C₄₉H₄₀BF₂N₅ 

Relevant academic research and scientific papers

Novel BODIPY-bridged cyclotriphosphazenes

Three new 2-component unsubstituted (4P), diiodo- (5P), and dibromo- (6P) distyryl-BODIPY-bridged cyclotriphosphazene dimers were designed and synthesized. The newly synthesized BODIPY-cyclotriphosphazene systems were characterized by 1 H, sup

Silica Nanoparticles with Up-conversion Fluorescence Based on Triplet-Triplet Annihilation Mechanism for Specific Recognition of Apoptosis Cells

Discrimination of live and apoptotic cells is a crucial task in the research of pharmacology, biology, pathology, and medicine science. Recently, up-conversion (UC) luminescent materials have appealed much attention due to their unique ability to convert low energy excitation photons to high energy ones. However, UC fluorescence has not been employed in the field of discrimination of live and apoptotic cells. We present a facile and costless St?ber method to fabricate robust silica nanoparticles (SiO2 UCNPs) exhibiting several merits, such as narrow size distribution and UC luminescence. SiO2 UCNPs could discriminate live and apoptosis cells by taking advantage of the unique surface property of SiO2 UCNPs for the first time. This work is also the first demonstration of the use of single photon excited UC fluorescence derived from nanoparticles for biological recognition of a specific type of cells.

Tumor-targeting, enzyme-activated nanoparticles for simultaneous cancer diagnosis and photodynamic therapy

Specific targeting towards tumors and the on-site activation of photosensitizers to diagnose tumors and reduce side effects for patients are currently the main challenges for photodynamic therapy (PDT) in the clinic. Herein, uniform diiodostyryl bodipy co

Triarylamine-BODIPY derivatives: A promising building block as hole transporting materials for efficient perovskite solar cells

In this work, the syntheses and characterization of four new TPA-BODIPY dyads as hole-transporting layers (HTLs) are reported. The photophysical and electrochemical properties of the dyads BTPA-I, BTPA-II, BTPA-III and BTPA-IV are investigated in solution and compared with the reference compounds BDP, BDP1, BDP2, TPA, A (triphenylamine) and B (4,4′-dimethoxitriphenylamine). The TPA-BODIPY derivatives strongly absorb visible light and upon photoexcitation at the BODIPY unit, these dyads undergo photoinduced electron transfer to form the corresponding charge-separated species, which was confirmed by solvatochromic measures of fluorescence. Their redox potentials and photophysical properties suggested that the new BTPAs derivatives showed a better ionization potential that free triphenylamines, which makes them promising candidates to use as hole transport layers (HTLs).

Optical Limiting Properties of 3,5-Dithienylenevinylene BODIPY Dyes at 532 nm

The optical limiting properties of a series of near infrared absorbing 3,5-dithienylenevinylene BODIPY (boron-dipyrromethene) dyes (1–3) that contain donor and acceptor moieties in their π-conjugation systems were studied by using the z-scan technique at

Diiodobodipy-styrylbodipy Dyads: Preparation and Study of the Intersystem Crossing and Fluorescence Resonance Energy Transfer

2,6-Diiodobodipy-styrylbodipy dyads were prepared to study the competing intersystem crossing (ISC) and the fluorescence-resonance-energy-transfer (FRET), and its effect on the photophysical property of the dyads. In the dyads, 2,6-diiodobodipy moiety was

An anthracene functionalized BODIPY derivative with singlet oxygen storage ability for photothermal and continuous photodynamic synergistic therapy

Singlet oxygen (1O2) generated from the photosensitization process within tumor tissues during photodynamic therapy (PDT) is self-limiting. Fractional delivery of light tends to be a better method for PDT. Herein, BDPIA with a high 1O2 quantum yield (QY) of 70% in DCM has an additional anthracene module for capturing 1O2, which would be useful in PDT. In the light cycle, the endoperoxide of anthracene is generated with singlet oxygen while in the dark cycle, the endoperoxide undergoes thermal cycloreversion to produce 1O2, regenerating the anthracene module. Therefore, the photodynamic process can continue in the dark period and the light cycles, promising their continuous phototherapy efficacy. In addition, BDPIA NPs in water exhibit a high photothermal conversion efficiency (η = 38.9%) for effective photothermal therapy. In vitro MTT assay shows that BDPIA NPs have a low half inhibitory concentration (IC50) of 6.293 μg mL-1 on HeLa cells. Furthermore, lentiviral vector transfected HeLa cell lines with red fluorescent proteins were used to perform real time in vivo fluorescence imaging guided phototherapy. The model can monitor the real-time uptake of BDPIA NPs. The results indicate that BDPIA NPs are capable of inhibiting cell proliferation even at a low dosage (0.2 mg kg-1) while the normal tissues (heart, liver, spleen, lung and kidney) suffer from no side effects. Our results demonstrate that BDPIA NPs with high phototoxicity, low dark toxicity and excellent bio-compatibility can be used as a potential photosensitizer for continuous photodynamic and photothermal synergistic therapy.

Circularly polarized luminescence of AIE-active chiral O-BODIPYs induced via intramolecular energy transfer

Two AIE-active chiral BINOL-based O-BODIPY enantiomers (R/S-5) were synthesized and showed mirror-image red-color CPL induced via intramolecular energy transfer. The chiroptical properties of the molecules indicate that the chirality of electronic ground

Self-Assembly of Novel Thiophene-Based BODIPY RuII Rectangles: Potential Antiproliferative Agents Selective Against Cancer Cells

Novel Ru (2+2) rectangles were designed and synthesized by self-assembly of a new thiophene-functionalized dipyridyl BODIPY ligand, BDPS, and ruthenium(II) precursors. The complexes exhibited dose-dependent antiproliferative activities against cancer cells, in which some compounds selectively kill cancer cells. The net fluorescence due to BODIPY allowed us to visualize their location inside cancer cells. Moreover, the metalla-rectangles displayed substantial propensity to bind with biomolecules.

Conjugated copolymer-photosensitizer molecular hybrids with broadband visible light absorption for efficient light-harvesting and enhanced singlet oxygen generation

We have developed conjugated copolymer-photosensitizer molecular hybrids (PFBDBP-IPBP) with a strong, broad (from 400 nm to ～700 nm) and continuous visible absorption. The photosensitizing ability of PFBDBP-IPBP was demonstrated to be higher than that of