1093868-91-7

Basic information

• Product Name: 2-(2-bromo-4-fluorophenyl)-4,4-dimethyl-2-oxazoline
• Synonyms: 2-(2-bromo-4-fluorophenyl)-4,4-dimethyl-2-oxazoline
• CAS NO: 1093868-91-7
• Molecular Weight: 272.117
• Mol File: 1093868-91-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-bromo-4-fluorophenyl)-4,4-dimethyl-2-oxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromo-4-fluorophenyl)-4,4-dimethyl-2-oxazoline(1093868-91-7)
• EPA Substance Registry System: 2-(2-bromo-4-fluorophenyl)-4,4-dimethyl-2-oxazoline(1093868-91-7)

Safety Data

• Hazardous Substances Data: 1093868-91-7(Hazardous Substances Data)

Upstream product

• 71171-94-3 2-(4-Fluorophenyl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 1006-41-3 2-bromo-4-fluorobenzoic acid 
• 104283-70-7 4,4-dimethyl-2-(4-fluorophenyl)oxazoline 
• 459-57-4 4-fluorobenzaldehyde 
• 124-68-5 2-Amino-2-methyl-1-propanol 
• 95383-36-1 2-bromo-4-fluorobenzoyl chloride 

Downstream Products

• 1093868-92-8 tert-butyl 3-(2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)-5-fluorophenyl)-3-oxopropyl(methyl)carbamate 
• 1093868-46-2 3-((S)-1-cyclohexyl-3-(methylamino)propan-2-yl)-1-(2-((S)-6-fluoro-1-(4-methoxybutyl)-3-oxoisoindolin-1-yl)ethyl)-1-methylurea 
• 1093869-25-0 C₃₂H₅₁FN₄O₅ 

Relevant articles and documents

Directed functionalization of halophenyl-2-oxazolines with TMPMgCl?LiCl

A variety of difunctionalized aryl-2-oxazolines were prepared from the reaction of halophenyl-2-oxazolines and TMPMgCl?LiCl to give an organomagnesium reagent, which was then treated with various electrophiles. The metalation step takes place under mild conditions, and this process al-lows for the isolation of the desired products in good yields. No isomeric or other benzyne-derived products were detected. The influence of the halogen substituents on the acidity of the aromatic hydrogen atoms was evaluated by using density functional theory (DFT) calculations.