1101-39-9Relevant academic research and scientific papers
Iron-Catalyzed Indolizine Synthesis from Pyridines, Diazo Compounds, and Alkynes
Douglas, Tim,Pordea, Anca,Dowden, James
, p. 6396 - 6399 (2017)
The iron(III)-catalyzed synthesis of indolizines from commercially available alkyne, pyridine, and diazo precursors is reported. This mild, expedient method is tolerant of various solvents and proceeds with as little as 0.25 mol % [Fe(TPP)Cl]. Significant
Efficient one-pot synthesis of 2-oxo-1,9a-dihydro-2H-pyrido[1,2-a] pyrimidine derivatives
Adib, Mehdi,Yavari, Hossine,Mollahosseini, Mehdi
, p. 1803 - 1805 (2004)
Pyridines react smoothly with dialkyl acetylenedicarboxylates in the presence of isocyanates to produce dialkyl 2-oxo-1,9a-dihydro-2H-pyrido[1,2-a] pyrimidine 3,4-dicarboxylates in excellent yields.
C-Silyl Derivatives of Quinolizines
Birkofer, Leonhard,Wahle, Bernd
, p. 2564 - 2573 (2007/10/02)
The cycloaddition of dimethyl acetylenedicarboxylate (1) to the C-silylated pyridines 2b - f leads to the corresponding partially very labile C-silylated tetramethyl 9aH-quinolizine-1,2,3,4-tetracarboxylates 3b - j, which are rearranged into the isomeric tetramethyl C-silyl-4H-quinolizine-1,2,3,4-tetracarboxylates 4b - g.From 4b - d the silylated dimethyl 3-methoxalyl-4-oxo-4H-quinolizine-1,2-dicarboxylates 6b - d are formed via the quinolizinium perchlorates, from which the perchlorate 5b was isolated.
