110166-26-2Relevant articles and documents
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Pozharskii,Konstantinchenko
, (1972)
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Direct and facile synthesis of 9-aminoacridine and acridin-9-yl-ureas
Borovlev, Ivan V.,Demidov, Oleg P.,Amangasieva, Gulminat A.,Avakyan, Elena K.
, p. 3608 - 3611 (2016)
The ability of urea anions to react as nucleophiles with acridine has been investigated. An effective SNH synthesis of 9-aminoacridine was developed using the urea/NaH/DMSO system. However, when mono substituted ureas containing bulky substituents or 1,1-dialkyl substituted ureas were used, products of the SNH reaction of alkyl carbamoyl amination were obtained. Single crystal structure and the tautomerism of selected compound were studied.
Synthesis and performance research of selenazole fluorescent dye compound
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Paragraph 0007; 0017, (2020/02/27)
The invention discloses synthesis and performance research of a selenazole fluorescent dye compound; benzoselenazole is used as a recognition group for detecting the HOCl level in cells, and a reliable method is provided for detecting the HOCl level in a biological system in real time. A probe disclosed by the invention has the technical effects that the probe can sensitively and selectively respond to HOCl and detect the HOCl level in tumor living cells, so that the HOCl level in the tumor living cells can be rapidly monitored, and a new method can be provided for early detection of tumors. Compared with other fluorescent compounds, the fluorescent reaction system containing the selenide functional group is simple, has the characteristics of high luminous efficiency, small background interference and the like, and is a fluorescent probe with a wide prospect.
Imine acridine derivative fluorescent probe as well as preparation method and application thereof in detection of MORAb-3-1 antibodies
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, (2018/11/22)
The invention discloses an imine acridine derivative fluorescent probe as well as a preparation method and application thereof in detection of MORAb-3-1 antibodies. A detection method of the MORAb-3-1antibody is established by combining specificities of antigens and antibodies. The detection method of the MORAb-3-1 antibody has the technical effects that 1, an imine acridine derivative biologicalprobe is combined with HSA (human serum albumin), and then combined with the MORAb-3-1 antibody for the first time, and the MORAb-3-1 antibody is observed under a fluorescent inverted microscope; 2,the combination of the probe and the antigen is judged by utilizing the photophysical and photochemistry natures; 3, the sensitivity is high, the operation is simple, convenient and rapid, and the accuracy is realized; compared with the traditional dye method, the advantages are more excellent. The formula is shown in the description.
