Tetrahedron Letters p. 703 - 706 (1987)
Update date:2022-09-26
Topics:
Bonadies, Francesco
Fabio, Romano Di
Gubbiotti, Andreina
Mecozzi, Sandro
Bonini, Carlo
A new strategy for the preparation of chiral β-hydroxy-δ-lactone inhibitors of HMGCoA reductase is outlined: in particular the compactin lactone moiety has been elaborated by asymmetric epoxidation of the appropriate allylic alcohol and subsequent introdu
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