1115-96-4

Basic information

• Product Name: N,N-DIMETHYLPIMELAMIDE
• Synonyms: N,N-dimethylenanthamide;nn-dimethylheptanamide;N,N-DIMETHYLPIMELAMIDE;TIMTEC-BB SBB008017;N,N-Dimethylenanthic acid amide
• CAS NO: 1115-96-4
• Molecular Formula: C₉H₁₉NO
• Molecular Weight: 157.25
• Mol File: 1115-96-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 220.4°C at 760 mmHg
• Flash Point: 83°C
• Appearance: /
• Density: 0.866g/cm³
• Vapor Pressure: 0.113mmHg at 25°C
• Refractive Index: 1.436
• PKA: -0.35±0.70(Predicted)
• CAS DataBase Reference: N,N-DIMETHYLPIMELAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DIMETHYLPIMELAMIDE(1115-96-4)
• EPA Substance Registry System: N,N-DIMETHYLPIMELAMIDE(1115-96-4)

Safety Data

• Hazardous Substances Data: 1115-96-4(Hazardous Substances Data)

Usage

General Description

N,N-Dimethylpimelamide is a chemical compound with the molecular formula C10H20N2O2. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. N,N-DIMETHYLPIMELAMIDE is an amide derivative of pimelic acid and contains two methyl groups attached to the nitrogen atom. N,N-Dimethylpimelamide is a white crystalline solid that is soluble in organic solvents and is stable under normal conditions. It is also known to have some antimicrobial properties and is used in the research and development of new drugs and agricultural products.

InChI:InChI=1/C9H19NO/c1-4-5-6-7-8-9(11)10(2)3/h4-8H2,1-3H3

Upstream product

• 111-14-8 oenanthic acid 
• 124-40-3 dimethyl amine 
• 592-41-6 1-hexene 
• 68-12-2 N,N-dimethyl-formamide 
• 18494-53-6 1-(piperidin-1-yl)heptan-1-one 
• 14062-78-3 N,N-dimethyl-4-toluamide 
• 506-59-2 N,N-dimethylammonium chloride 
• 2528-61-2 Heptanoic acid chloride 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 541-41-3 chloroformic acid ethyl ester 
• 90467-78-0 Ethyl thioenanthate 
• 110-53-2 1-Bromopentane 
• 127-19-5 N,N-dimethyl acetamide 

Downstream Products

• 111-71-7 heptanal 
• 111-70-6 n-heptan1ol 
• 18494-53-6 1-(piperidin-1-yl)heptan-1-one 
• 14062-78-3 N,N-dimethyl-4-toluamide 
• 89789-82-2 (4-Benzyloxycarbonylamino-undecyl)-carbamic acid benzyl ester 

Relevant articles and documents

Utility of dysprosium as a reductant in coupling reactions of acyl chlorides: The synthesis of amides and diaryl-substituted acetylenes

Reduction of acyl chlorides with dysprosium metal has been studied. The reducing ability of dysprosium metal is solvent-dependent. Dysprosium metal, which requires neither any additive nor pretreatment, can promote the cross-coupling of acyl chlorides in DMF or DEF to give amides in good yields. When the reaction was performed in N,N-dimethylacetamide, the reductive self-coupling reaction of aroyl chloride took place smoothly and afforded the diaryl-substituted acetylenes in moderate to good yield.

Catalytic Enantioselective α-Fluorination of 2-Acyl Imidazoles via Iridium Complexes

The first highly enantioselective α-fluorination of 2-acyl imidazoles utilizing iridium catalysis has been accomplished. This transformation features mild conditions and a remarkably broad substrate scope, providing an efficient and highly enantioselective approach to obtain a wide range of fluorine-containing 2-acyl imidazoles which are found in a variety of bioactive compounds and prodrugs. A large scale synthesis has also been tested to demonstrate the potential utility of this fluorination method.

Copper-catalyzed oxidative coupling of carboxylic acids with N,N-dialkylformamides: An approach to the synthesis of amides

A new synthetic approach for amide bond formation through the oxidative coupling of N,N-dialkylformamides with carboxylic acids was achieved by using a copper catalyst. Furthermore, this method was applied in the coupling of chiral amino acids in which the stereochemistry was retained in the resulting amide products. A new synthetic approach to amide bond formation through the oxidative coupling of N,N-dialkylformamides with carboxylic acids was achieved by using a copper catalyst and aqueous tert-butyl hydroperoxide (TBHP) as a sacrificial oxidant. Furthermore, this method was applied in the coupling of chiral amino acids in which the stereochemistry was retained in the resulting amide products. Copyright