111594-58-2

Usage

Uses

1. Used in Pharmaceutical Industry:
Silane, [[(1a,3b,5E,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraene-1,3-diyl]bis(oxy)]bis[(1,1-dimethylethyl)dimethyl(9CI) is used as an intermediate in the synthesis of biologically active vitamin D2 metabolite for the pharmaceutical industry. Its role in the synthesis process is crucial for the development of vitamin D2-based medications, which have various applications in treating and preventing health conditions related to vitamin D deficiency.
2. Used in Chemical Research:
In the field of chemical research, Silane, [[(1a,3b,5E,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraene-1,3-diyl]bis(oxy)]bis[(1,1-dimethylethyl)dimethyl(9CI) serves as a valuable compound for studying the properties and behavior of complex organic molecules. Its unique structure allows researchers to explore various aspects of chemical reactions and interactions, contributing to the advancement of knowledge in organic chemistry.
3. Used in Material Science:
Silane, [[(1a,3b,5E,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraene-1,3-diyl]bis(oxy)]bis[(1,1-dimethylethyl)dimethyl(9CI) may also find applications in material science, particularly in the development of new materials with specific properties. Its unique molecular structure could potentially be utilized in the creation of novel materials with enhanced characteristics, such as improved stability, reactivity, or biocompatibility.

InChI:InChI=1/C40H72O2Si2/c1-28(2)29(3)19-20-30(4)35-23-24-36-32(18-17-25-40(35,36)12)21-22-33-26-34(41-43(13,14)38(6,7)8)27-37(31(33)5)42-44(15,16)39(9,10)11/h19-22,28-30,34-37H,5,17-18,23-27H2,1-4,6-16H3/b20-19+,32-21+,33-22+/t29-,30+,34+,35+,36-,37-,40+/m0/s1

Upstream product

• 87417-26-3 (3S,6S)-(tert-butyldimethylsilyloxy)-9,10-seco-ergosta-5,7(E),10⁽¹⁹⁾,22(E)-tetraene SO₂-adduct 
• 104846-62-0 tert-Butyl-dimethyl-{(S)-4-methylene-3-[2-[(1R,7aR)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-cyclohexyloxy}-silane 
• 112670-78-7 (R)-5-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-3-[2-[(1R,7aR)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-cyclohexanol 
• 170081-43-3 SO2-adduct of 3(S)-<(tert-butyldimethylsilyl)oxy>-9,10-secoergosta-5,7(E),10(19),22(E)-tetraene 
• 104846-62-0 (5E)-vitamin D₂ tert-butyldimethylsilyl ether 
• 87680-65-7 (S)-3-[(1R,3aS,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ⁶-benzo[c]thiophen-5-ol 
• 50-14-6 Calciferol 
• 74007-20-8 1α-hydroxy-5,6-trans-vitamin D₂ 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 112670-78-7 1(S),3(R)-3-(tert-butyldimethylsilyl)-9,10-secoergosta-5(E),7(E),10⁽¹⁹⁾,22(E)-tetraene-1-ol 
• 115540-27-7 1(S),3(R)-3-(tert-butyldimethylsilyl)-9,10-secoergosta-5(E),7(E),10⁽¹⁹⁾,22(E)-tetraene-1-ol 
• 87417-26-3 (3S,6R)-(tert-butyldimethylsilyloxy)-9,10-seco-ergosta-5,7(E),10⁽¹⁹⁾,22(E)-tetraene SO₂ adduct 
• 247900-07-8 (7Z)-Vitamin D₂ 

Downstream Products

• 111594-60-6 (S)-5-[2-[(1R,3aS,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-4-pentyl-cyclohex-3-enol 
• 112670-82-3 (1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(E)-ylidene]-eth-(E)-ylidene]-7a-methyl-1-((S)-1-methyl-2-methylselanyl-ethyl)-octahydro-indene 
• 112670-81-2 (1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(E)-ylidene]-eth-(E)-ylidene]-7a-methyl-1-((S)-1-methyl-2,2-bis-methylselanyl-ethyl)-octahydro-indene 
• 112670-83-4 (1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(E)-ylidene]-eth-(E)-ylidene]-1-((1S,2R)-1,5-dimethyl-2-methylselanyl-hexyl)-7a-methyl-octahydro-indene 
• 112670-83-4 (1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(E)-ylidene]-eth-(E)-ylidene]-1-((1S,2S)-1,5-dimethyl-2-methylselanyl-hexyl)-7a-methyl-octahydro-indene 
• 184851-16-9 C₄₀H₇₂O₂Si₂ 
• 1255151-20-2 1(S),3(R)-bis(tert-butyldimethylsilyloxy)-20(R)-(3′-isopropyl-3′-oxypropyl)-9,10-secopregna-5(E),7(E),10(19)-triene 
• 266686-81-1 (6S)- and (6R)-SO₂ adducts of 1(S),3(R)-bis(tert-butyldimethylsilyloxy)-20(S)-formyl-9,10-secopregna-5,7(E),10⁽¹⁹⁾-triene 
• 57333-96-7 tacalcitol 
• 57333-95-6 1alpha,24(S)-Dihydroxyvitamin D₃ 
• 184851-16-9 1(S),3(R)-bis(tert-butyldimethylsiloxy)-9,10-secoergosta-5(E),7(E),10⁽¹⁹⁾,22(E)-tetraene 
• 87649-67-0 doxercalciferol 
• 115648-67-4 1(S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-20(R)-formyl-9,10-secopregna-5(E),7(E),10(19)-triene 
• 112828-13-4 (5E,7E)-(1S,3R,20S)-1,3-bis<<(1,1-dimethylethyl)dimethylsilyl>oxy>-20-methyl-9,10-secopregna-5,7,10(19)-trien-21-al 

Relevant academic research and scientific papers

Allylic Hydroxylation of Vitamin D with Mercury(II) trifluoroacetate

Treatment of vitamin D with Hg(OCOCF3)2 results in formation of the isovitamin D derivative 2, which can be converted into C-1 hydroxylated 5E vitamin D derivatives.Key Words: Allylic hydroxylation; mercurytrifluoroacetate; isovitamin D derivatives; vitamin D derivatives; 199Hg NMR.

A calcitriol synthesis of intermediates method

The invention discloses a calcitriol intermediate compound preparation method, which belongs to the drug synthesis and organic compound synthesis technology field. The invention wide sources of raw materials are easy, simple and safe operation, environmen

Enantiomeric impurity PY2 of tacalcitol and preparation method and application thereof

The invention discloses an enantiomeric impurity PY2 of tacalcitol, i.e., (1 alpha, 3 beta, 5Z, 7E, 24S)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol, and a preparation method thereof, and belongsto the technical field of chemical pharmaceutical. The high-purity relevant impurity PY2 of the tacalcitol, which is disclosed by the invention, can be used as an impurity standard substance in the tacalcitol finished product detection analysis so as to promote accurate positioning and nature determination of the tacalcitol finished product detection analysis on the impurity and benefit reinforcement of control on the impurity, thereby improving quality of a tacalcitol finished product. The method provided by the invention has the advantages that the raw materials are cheap and easy to obtain, the operation is simple, the reproducibility is good in and the HPLC (High Performance Liquid Chromatography) purity is greater than or equal to 99.5%.

Synthesis of 24(28)-methylene-1α-hydroxyvitamin D3, a novel vitamin D3 analogue

24(28)-Methylene-1α-hydroxyvitamin D3 was synthesised in 13 steps from vitamin D2. The key step of the synthesis involved the Wittig-Horner olefination of a nor-vitamin D2 aldehyde with diethylphosphono-3-methyl-2-butanone

Development of an improved process for doxercalciferol via a continuous photochemical reaction

Doxercalciferol (1α-hydroxyvitamin D2) is a commercially approved vitamin D derivative used to treat chronic kidney disease (CKD) patients whose kidneys cannot metabolically introduce a hydroxyl group at C1. A new process for the production of doxercalcif

Synthesis of a Biologically Active Vitamine-D2 Metabolite

The synthesis of 1α,25,28-trihydroxyvitamin-D2 (1) from vitamin-D2 is described.Approaches to the upper side-chain synthon via the chiral sulfone 15, prepared either through the enzymatic resolution of 10 or the opening of the optica