Allylic Hydroxylation of Vitamin D with Mercury(II) trifluoroacetate

Article abstract of DOI:10.1016/S0040-4039(00)92212-3

Treatment of vitamin D with Hg(OCOCF3)2 results in formation of the isovitamin D derivative 2, which can be converted into C-1 hydroxylated 5E vitamin D derivatives.Key Words: Allylic hydroxylation; mercurytrifluoroacetate; isovitamin D derivatives; vitamin D derivatives; 199Hg NMR.