112089-54-0

Upstream product

• 100-39-0 benzyl bromide 
• 610-78-6 3-nitro-4-chlorophenol 
• 106014-83-9 2-[4-(benzyloxy)-2-nitrophenyl]propane-1,3-diol 
• 79035-13-5 4-benzyloxy-2-nitro-chlorobenzene 
• 112089-51-7 diethyl <4-(benzyloxy)-2-nitrophenyl>malonate 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 
• 106014-84-0 2-<2-amino-4-(benzyloxy)phenyl>propane-1,3-diol 
• 185985-43-7 (1-Methanesulfonyl-6-methoxy-2,3-dihydro-1H-indol-3-yl)-methanol 
• 185985-39-1 N-allyl-N-(2-iodo-5-methoxyphenyl)methanesulfonamide 
• 952013-86-4 1-Methanesulfonyl-6-methoxy-3-methylene-2,3-dihydro-1H-indole 
• 79035-19-1 3-acetoxymethyl-2,3-dihydro-1-methylsulfonyl-6-methoxyindole 
• 108-24-7 acetic anhydride 
• 106014-85-1 6-(benzyloxy)-1-(methylsulfonyl)-3-<<(methylsulfonyl)oxy>methyl>indoline 
• 127-09-3 sodium acetate 

Downstream Products

• 173368-74-6 3-(tert-Butyl-diphenyl-silanyloxymethyl)-1-methanesulfonyl-2,3-dihydro-1H-indol-6-ol 
• 173368-73-5 6-Benzyloxy-3-(tert-butyl-diphenyl-silanyloxymethyl)-1-methanesulfonyl-2,3-dihydro-1H-indole 
• 173368-75-7 Acetic acid (2S,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[3-(tert-butyl-diphenyl-silanyloxymethyl)-1-methanesulfonyl-2,3-dihydro-1H-indol-6-yloxy]-tetrahydro-pyran-3-yl ester 
• 104636-96-6 2-acetyl-1,2,8,8a-tetrahydro-7-methylcyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one 
• 112089-53-9 5-(benzyloxy)-1,2,3,6,7,8-hexahydro-3-(methylsulfonyl)-8-(methylthio)-7-oxobenzo[1,2-b:4,3-b']dipyrrole-1-methanol acetate 
• 108833-12-1 5-(benzyloxy)-1,2,3,6,7,8-hexahydro-8-methyl-3-(methylsulfonyl)-8-<(2-hydroxyethyl)thio>-7-oxobenzo<1,2-b:4,3-b'>dipyrrole-1-methanol acetate 
• 108833-10-9 5-amino-6-(benzyloxy)-2,3-dihydro-1-(methylsulfonyl)-1H-indole-3-methanol acetate 
• 101134-89-8 5-(benzyloxy)-1,2,3,6-tetrahydro-8-methyl-3-(methylsulfonyl)benzo<1,2-b:4,3-b'>dipyrrole-1-methanol 
• 108833-11-0 5-(benzyloxy)-1,2,3,6,7,8-hexahydro-8-methyl-3-(methylsulfonyl)-8-(methylthio)-7-oxobenzo<1,2-b:4,3-b'>dipyrrole-1-methanol acetate 
• 112243-83-1 5-(benzyloxy)-1,2,3,6-tetrahydro-8-methylbenzo<1,2-b:4,3-b'>dipyrrole-1-methanol 
• 112089-71-1 (+/-)-(1R*)-5-(benzyloxy)-3-<(tert-butyloxy)carbonyl>-1-(hydroxymethyl)-8-methyl-1,2-dihydro-3H-pyrrolo<3,2-e>indole 
• 112089-72-2 5-(benzyloxy)-1,2,3,6-tetrahydro-8-methyl-3-acetylbenzo<1,2-b:4,3-b'>dipyrrole-1-methanol 
• 105622-88-6 C₂₂H₁₉N₃O₃ 
• 112089-74-4 5-(benzyloxy)-1,2,3,6-tetrahydro-8-methyl-3-acetylbenzo<1,2-b:4,3-b'>dipyrrole-1-methanol 1-methanesulfonate 

Relevant academic research and scientific papers

Tumorselektiv aktivierbare Prodrugs des Cytostaticums CC-1065

Keywords: Cytostatica; Enzyme; β-Galactosidase; β-Glucosidase; Heck-Reaktionen

Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065

The synthesis, physicochemical properties, and biological activities of a series of novel spiro cyclopropyl compounds, modeled on the potent antitumor antibiotic CC-1065 (1), are described. Many of these synthetic analogues are significantly more effectiv

Total Synthesis of U-71,184, A Potent New Antitumor Agent Modeled on CC-1065

The synthesis of U-71,184 (2), a highly potent analog of the novel antitumor antibiotic CC-1065, is described, the penultimate step of which involves the unmasking of a p-hydroxy phenethyl mesylate, which undergoes facile intramolecular elimination to aff