1121-21-7

Basic information

• Product Name: 1,2-Dichlorocyclohexane
• Synonyms: Cyclohexylene dichloride
• CAS NO: 1121-21-7
• Molecular Formula: C₆H₁₀Cl₂
• Molecular Weight: 153.0496
• Mol File: 1121-21-7.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 198°Cat760mmHg
• Flash Point: 66.1°C
• Appearance: /
• Density: 1.14g/cm³
• CAS DataBase Reference: 1,2-Dichlorocyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Dichlorocyclohexane(1121-21-7)
• EPA Substance Registry System: 1,2-Dichlorocyclohexane(1121-21-7)

Safety Data

• Hazardous Substances Data: 1121-21-7(Hazardous Substances Data)

Usage

Description

1,2-Dichlorocyclohexane, with the molecular formula C6H10Cl2, is a colorless liquid chemical compound characterized by a chloroform-like odor. It is insoluble in water and recognized for its role as an intermediate in various industrial applications, particularly in the synthesis of agrochemicals and pharmaceuticals.

Uses

Used in Agrochemical Production:
1,2-Dichlorocyclohexane is used as a synthetic intermediate for the production of agrochemicals, contributing to the development of compounds that protect crops from pests and diseases, thereby ensuring agricultural productivity.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1,2-Dichlorocyclohexane serves as a key intermediate, facilitating the synthesis of various medicinal compounds that address a range of health conditions.
Used as a Solvent:
1,2-Dichlorocyclohexane is utilized as a solvent in certain chemical processes, leveraging its properties to dissolve other substances and enable reactions to occur.
Used in Organic Compound Synthesis:
Beyond its direct applications, 1,2-Dichlorocyclohexane is also employed as a synthetic intermediate in the production of other organic compounds, expanding its utility across multiple chemical synthesis pathways.
Environmental Considerations:
Given its toxicity to aquatic organisms and potential for causing long-term environmental harm, 1,2-Dichlorocyclohexane necessitates careful handling and disposal to mitigate risks to both human health and ecological systems.

Upstream product

• 110-83-8 cyclohexene 
• 3135-74-8 chlorourea 
• 7732-18-5 water 
• 286-20-4 cyclohexane-1,2-epoxide 
• 1122-60-7 1-nitrocyclohexane 
• 108-93-0 cyclohexanol 
• 108-94-1 cyclohexanone 
• 542-18-7 cyclohexyl chloride 
• 110-82-7 cyclohexane 
• 56-23-5 tetrachloromethane 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 65411-49-6 tetrabutylammonium methanesulfonate 
• 7182-86-7 tetrabutylammonium p-toluenesulfonate 

Downstream Products

• 110-83-8 cyclohexene 
• 318292-43-2 1,2-cyclohexane dicarboxylic acid di-isononylester 
• 87-82-1 hexabromobenzene 
• 84-14-0 1,2-diphenyl-cyclohexane 
• 16069-36-6 perhydrodibenzo-18-crown-6 

Relevant articles and documents

Electrochemical Acylation of Some Cyclic Olefins by Using Aluminium Anode

The electrochemical acylation of cyclohexene, cycloheptene and their 1-methyl derivatives produces alkyl-cycloalkenyl ketones in good yields.The unsubstituted cycloalkenes give α,β-unsaturated ketones, whereas the 1-substituted derivatives yield mixtures of α,β- and β,γ-unsaturated ketones in which the latter products are predominant.

α-ELIMINATION OF ORGANIC HALIDES FROM ORGANOTELLURIUM(IV) HALIDES

Three types of α-elimination (oxidative, photolytic, and thermal) of organotellurium(IV) halides to give organic halides have been disclosed.Treatment of organotellurium(IV) halides with some oxidants, preferably t-butyl hydroperoxide in 1,4-dioxane, acet

Highly selective halogenation of unactivated C(sp3)-H with NaX under co-catalysis of visible light and Ag@AgX

The direct selective halogenation of unactivated C(sp3)-H bonds into C-halogen bonds was achieved using a nano Ag/AgCl catalyst at RT under visible light or LED irradiation in the presence of an aqueous solution of NaX/HX as a halide source, in air. The halogenation of hydrocarbons provided mono-halide substituted products with 95% selectivity and yields higher than 90%, with the chlorination of toluene being 81%, far higher than the 40% conversion using dichlorine. Mechanistic studies demonstrated that the reaction is a free radical process using blue light (450-500 nm), with visible light being the most effective light source. Irradiation is proposed to cause AgCl bonding electrons to become excited and electron transfer from chloride ions induces chlorine radical formation which drives the substitution reaction. The reaction provides a potentially valuable method for the direct chlorination of saturated hydrocarbons.

Visible light induced oxygenation of alkenes with water sensitized by silicon-porphyrins with the second most earth-abundant element

Silicon as the second most abundant element on Earth was effectively utilized as the central atom in the porphyrin to induce photochemical oxygenation of alkenes as the first example of photocatalytic reaction through activation of water molecule in the presence of K2PtCl6 as an electron acceptor. Oxygen atom of water was confirmed to be incorporated in the oxygenated product by the photoreaction with H218O. The excited triplet state of silicon porphyrin was revealed to be responsible for the photochemical oxygenation. The one-electron oxidized silicon porphyrin was predicted by DFT calculation to have its spin population mostly on the axially ligated hydroxyl oxygen atom. The oxyl radical character of the axial ligand could rationalize the oxygenation reaction.