87-82-1Relevant articles and documents
A six-bromophenylacetic synthetic method (by machine translation)
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Paragraph 0014-0017, (2019/05/29)
The invention relates to a six-bromophenylacetic synthetic method, which belongs to the technical field of synthesis of bromine-containing flame-retardant agent. The french law is bromine is added in the glass lining reaction kettle, anhydrous aluminum chloride and the fuming sulfuric acid, into the grooves in the high benzene; actuating the stirring, the reaction water bath for heating, to maintain the temperature in the kettle not exceeding 50 °C, starting to drop [...], [...] acceleration control in each 35 - 45 minutes of the uniform speed drop end 48 - 52 kg benzene, reaction, system thermal insulation, discharge within the system of hydrogen bromide; to adding pure water in the kettle, to inject the steam makes the steam raised in the reactor, until the residual bromine is all boil off, the product of the reaction in the reaction vessel is a milky white crystal changes by the red; cooling to room temperature, filtered, the filter cake is washed and dried to get the product. This invention adopts the anhydrous aluminum chloride as catalyst, the catalytic effect is better, reaction temperature requirement is low, the product yield has been raised by 10% the left and right, at the same time effectively reducing the use of organic solvent, more environmental protection and safety. (by machine translation)
Thermal Stability Studies on a Homologous Series of Nitroarenes
Oxley, Jimmie C.,Smith, James L.,Ye, Hong,McKenney, Robert L.,Bolduc, Paul R.
, p. 9593 - 9602 (2007/10/02)
The thermal stabilities of a number of nitroarenes were examined in solution and in condensed phase.In general, increasing the number of nitro groups decreased thermal stability.Changing the substituent on 1-X-2,4,6-trinitrobenzene from X = H to NH2 to CH3 to OH accelerated decomposition; this effect was attributed to increased ease of intramolecular proton transfer to an ortho nitro group, thus weakening the carbon-nitrogen bond.In solution, the effect of increasing substitution from n = 1 to n = 3 on Xn(NO2)3C6H3-n was uniformly that of decreasing the thermal stability of the species.However, in condensed phase, results suggested that crystal habit may be more important than molecular structure; for X = Br, CH3, and NH2, the more substituted species was the more stable.
BROMINATION OF DEACTIVATED AROMATIC COMPOUNDS
Andrievskii, A.M.,Gorelik, M.V.,Avidon, S.V.,Al'tman, E.Sh.
, p. 1519 - 1524 (2007/10/02)
Unreactive aromatic compounds can be brominated with high yields by the action of bromine and nitric acid or another oxidizing agent (iodic acid, hydrogen peroxide, etc.) in concentrated sulfuric acid or oleum.Bromination in the presence of nitric acid has lower substrate selectivity than the concurrent nitration.Moderately deactivated aromatic substrates are nitrated initially, whereas inactive substrates are brominated.It is suggested that the electrophilic brominating agent is sulfohypobromite in the form of a complex with sulfuric acid.
