115-33-3 Usage
Originator
Lavema,Winthrop,US,1959
Uses
Different sources of media describe the Uses of 115-33-3 differently. You can refer to the following data:
1. Oxyphenisatin Diacetate is the pro-drug of Oxyphenisatin (O876965). Results confirm that Oxyphenisatin Diacetate inhibits the growth of breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.
2. Laxative.
Manufacturing Process
235 gravimetrical parts of acetic acid anhydride (90%) are poured over 106 gravimetrical parts of diphenolisatin (Berichte der Deutschen Chemischen Gesselschsft, 18, 1885, p. 2641) and the mixture is heated on the water-bath while stirring. The solid starting material temporarily dissolves almost entirely and shortly afterwards the reaction product turns into a crystalline paste. In order to complete the reaction the heating on the water-bath is continued for a short time and then the whole is left to get cold. The reaction product may, for instance, be separated in the following manner: To the cold reaction mixture is gradually added about the same volumetrical quantity of alcohol; in this manner the excess of acetic acid anhydride is destroyed and the paste becomes thinner. Then the fluid is drawn off and the product washed with alcohol. For complete cleansing another extraction is made with warm alcohol and the product crystallized, for instance, from 10 parts of acetic acid. The product represents a light, fine crystalline powder, which is difficultly soluble or even insoluble in the usual organic solvents. Its melting point lies at 242°C.
Brand name
Isocrin (Parke-Davis); Lavema (Sterling
Winthrop);Acelax;Acetalax;Alophen pills;Ameiax;Api-slender;Artzone;Belloform;Biivectan;Bisflatan;Boxogetten;Brocatine;Buta pirone;Buteril;Butofen;Butolfen;Bydolax;Chlofel;Chur-lax;Ciracen;Cirotex;Cirotyl;Contax;Critex;Curolax;Darmoletten;Deililax;Dialose plus;Diasatin;Ditinil;Ditmedol;Eulaxin;Evac-u-lax;Ex-lax pills;Febutolo;Fibutrox;Fim-a-mint;Fin-a-mint gum;Fisiolax;Flib 518;Inlax;Ipebutona;Isaaxan;Isaphenyn;Izaman;Laveman;Laxan-vomoxin;Laxaseptol;Laxem;Laxnormal;Laxocoleva;Laxon;Laxos;Laxyl;Med-laxan;Menabil complex;Muxol;Naleran;Neocervulax;Neo-favmadol;Neo-soldana;Nourilax;Nurilaksi;Obstilax;Otone;Oxybutazone;Phlogase;Phlogistol;Phlogont;Potsilo;Promassoletten;Prusol;Rheumapax;Rivolax;Schokilax;Syndian;Tanderil-alka;Tete-lax;Validil.
Therapeutic Function
Laxative
World Health Organization (WHO)
Oxyphenisatine acetate was widely used as a laxative after its
cathartic activity was first described in 1925. In 1969 its use was first associated
with cases of acute and chronic liver disease. This association is considered by
some, but not all, national drug regulatory authorities to warrant the withdrawal
from the market of preparations containing oxyphenisatine and its derivatives.
Check Digit Verification of cas no
The CAS Registry Mumber 115-33-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 115-33:
(5*1)+(4*1)+(3*5)+(2*3)+(1*3)=33
33 % 10 = 3
So 115-33-3 is a valid CAS Registry Number.
InChI:InChI=1/C24H19NO5/c1-15(26)29-19-11-7-17(8-12-19)24(18-9-13-20(14-10-18)30-16(2)27)21-5-3-4-6-22(21)25-23(24)28/h3-14H,1-2H3,(H,25,28)