115-96-8 Usage
Description
Tris(2-chloroethyl) phosphate, also known as TCEP, is a colorless, odorless liquid with a neutral pH. It is a trialkyl phosphate that is the tris(2-chloroethyl) ester of phosphoric acid. Tris(2-chloroethyl) phosphate is slightly water-soluble and combustible, making it a versatile chemical with various applications across different industries.
Uses
Used in Environmental Monitoring:
Tris(2-chloroethyl) phosphate is used as a sampling agent for dynamic air sampling of airborne organophosphate triesters. This application utilizes a solid-phase microextraction device to detect and monitor the presence of these potentially harmful compounds in the environment.
Used in Human Health Research:
In the field of human health research, Tris(2-chloroethyl) phosphate is used as a marker for a human urinary organophosphate flame retardant metabolite. This application aids in understanding the exposure and potential health effects of organophosphate flame retardants in humans.
Used in Chemical Synthesis:
Due to its chemical properties, Tris(2-chloroethyl) phosphate can be used as an intermediate in the synthesis of various compounds, particularly in the pharmaceutical and agrochemical industries. Its reactivity and stability make it a valuable component in the development of new products.
Used in Flame Retardants:
Tris(2-chloroethyl) phosphate is also utilized as a component in the formulation of flame retardants. Its combustibility and chemical properties make it suitable for use in materials that require enhanced fire resistance, such as plastics, textiles, and electronic components.
Reactivity Profile
Tris(2-chloroethyl) phosphate is incompatible with strong oxidizing agents and strong bases.
Safety Profile
Poison by
intraperitoneal route. Moderately toxic by
ingestion. Experimental reproductive
effects. Questionable carcinogen with
experimental tumorigenic data. A skin and
eye irritant. Combustible when exposed to
heat or flame. When heated to
decomposition it emits very toxic fumes of
POx and Cl-. See also PHOSPHATES,
CHLORIDES, and ESTERS.
Check Digit Verification of cas no
The CAS Registry Mumber 115-96-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 115-96:
(5*1)+(4*1)+(3*5)+(2*9)+(1*6)=48
48 % 10 = 8
So 115-96-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H12Cl3O4P/c1-4(7)11-14(10,12-5(2)8)13-6(3)9/h4-6H,1-3H3
115-96-8Relevant articles and documents
Epoxy ether cleaving reactions catalyzed by supporting Lewis acidic ionic liquid
Zhi, Hui Zhen,Shi, Hong Li,Hu, Yun,Xia, Ke Dan,Zhang, Peng,Yang, Jin Fei
, p. 1217 - 1220,4 (2020/09/16)
Lewis acidic ionic liquids were used to catalyze the reaction of epoxypropane with POCl3. Considering the lower cost and catalytic activities, we concluded that [Et3NH]Cl/AlCl3 was the most attractive ionic liquid from an economical point of view. But it would be easily inactivated because of sensitive to water and air. Moreover, it could not be reused easily because of difficulty recovery in the reaction. However, supporting [Et3NH]Cl/AlCl3 catalyst could resolve above problems. Supporting [Et3NH]Cl/AlCl3 catalyst could be separated by filter easily and reused 5 times in 98% yield. Furthermore, the catalyst was applicable to other epoxy ether cleaving reactions.
'Antispectrochemical' Behaviour of Cobalt(II) and Nickel(II) Chelates of Substituted Trialkylphosphates
Narula, Suraj P.,Kumar, Suniti,Bharadwaj, S. K.,Sharma, Rajeev
, p. 404 - 406 (2007/10/02)
The chelates of the type M2 have been prepared by the solvolysis of the corresponding divalent metal chlorides or acetate by respective trialkylphosphates.While the cobalt(II) derivatives are tetrahedral with two (RO)2P(O)2 chelating groups, the nickel(II) derivatives have a distorted octahedral geometry resulting from the possible participation of the ethereal oxygen of the alkoxy group.The organophosphate chelating groups reveal 'antispectrochemical behaviour' in these systems.