116429-08-4Relevant academic research and scientific papers
Alkoxide-catalyzed addition of alkyl carbonates across alkynes-stereoselective synthesis of (: E)-β-alkoxyacrylates
Wendling, Timo,Risto, Eugen,Erb, Benjamin,Goo?en, Lukas J.
supporting information, p. 643 - 646 (2017/08/15)
Dialkyl carbonates were found to regio- and stereoselectively add to terminal alkynes in the presence of catalytic amounts of potassium methoxide. Various synthetically meaningful aryl- and heteroaryl-substituted (E)-β-alkoxyacrylates were thus obtained i
SYNTHESIS OF 3-N-ALLYL-6-ALKYL-2-THIOURACILS
Turski, K.,Draminski, M.
, p. 1591 - 1596 (2007/10/02)
The title compounds were synthesized by the reaction of N-allylthiourea with 1.The use in reaction dimethylacetal of 1h give better results.That fact support our suggestion about the reason of troubles in condensation 1h in alkaline conditions.NMR and UV
Metalation of Alkynes. Part 2. Behaviour of Alkynes with Mercury(II)Acetate in Methanol: a Systematic Reinvestigation
Bassetti, Mauro,Floris, Barbara
, p. 227 - 234 (2007/10/02)
The reaction of a series of alkynes with mercury(II)acetate, both in equimolar and catalytic amounts, were investigated in methanol.Hex-1-yne, oct-1-yne, oct-4-yne, 1,4-diacetoxybut-2-yne, methyl oct-2-ynoate, methyl 3-phenylpropynoate, oct-2-ynoic acid, phenylpropynoic acid, oct-1-yn-3-ol, 1-ethynylcyclohexanol, 1-ethynylcyclohexamine, phenylethyne, diphenylethyne, and ethynylferrocene were the examined substrates.The non-mercuriated products from the reaction were the corresponding vinyl ether, dialkoxyalkane, and ketone, isolated under preparative conditions.The presence of 0.1percent toluene-p-sulphonic acid increased the reactivity.The reactions of oct-1-yne and oct-4-yne were studied in detail by following with time the formation of the products under a variety of conditions, and a mechanistic scheme was drawn.For comparison, styrene, trans-oct-4-ene, and trans-β-methylstyrene were treated with 5 molpercent mercury(II) acetate.The reaction of alkenes was found to be non-catalytic.
