116505-07-8

Basic information

• Product Name: 2-cyclohexylpropanoyl chloride
• Synonyms: 2-cyclohexylpropanoyl chloride
• CAS NO: 116505-07-8
• Molecular Weight: 174.671
• Mol File: 116505-07-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-cyclohexylpropanoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclohexylpropanoyl chloride(116505-07-8)
• EPA Substance Registry System: 2-cyclohexylpropanoyl chloride(116505-07-8)

Safety Data

• Hazardous Substances Data: 116505-07-8(Hazardous Substances Data)

Upstream product

• 6051-13-4 2-cyclohexylpropanoic acid 
• 31042-01-0 methyl (1-hydroxy-α-methylcyclohexane)acetate 
• 3451-36-3 (2R)-2-cyclohexylpropanoic acid 
• 5292-21-7 Cyclohexylacetic acid 
• 14352-61-5 methyl cyclohexylacetate 
• 108-94-1 cyclohexanone 
• 62184-70-7 methyl 2-(1-cyclohexenyl)propanoate 
• 77124-22-2 2-cyclohexylidenepropanoic acid 
• 40556-79-4 methyl 2-cyclohexylpropionate 

Downstream Products

• 28523-32-2 (R)-2-cyclohexyl-propionic acid amide 
• 1534433-39-0 2-cyclohexyl-N-(quinolin-8-yl)propanamide 
• 1534433-51-6 2-cyclohexyl-3-(4-methoxyphenyl)-N-(quinolin-8-yl)propanamide 
• 1425052-38-5 2-cyclohexyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)propanamide 
• 185199-40-0 3-cyclohexyl-1,3-dimethyloxindole 
• 20474-46-8 cyclohexyl-3 butanone-2 
• 116505-08-9 (5S,6R)-6-((R)-1-Cyclohexyl-ethyl)-5-methyl-4-pyrrolidin-1-yl-5,6-dihydro-pyran-2-one 
• 116505-08-9 (5S,6R)-6-((S)-1-Cyclohexyl-ethyl)-5-methyl-4-pyrrolidin-1-yl-5,6-dihydro-pyran-2-one 
• 65426-80-4 2-Cyclohexyl-propancarbonsaeure-p-nitrophenylester 

Relevant articles and documents

Catalytic enantioselective desymmetrization of cyclobutane-1,3diones by carbonyl-amine condensation

A chiral phosphoric acid-catalyzed enantioselective condensation of 2,2-disubstituted cyclobutane-1,3-diones with a primary amine is described. This reaction offered a mild and efficient protocol for constructing quaternary carbon-containing cyclobutanes

Pd(II)-Catalyzed Direct Sulfonylation of Unactivated C(sp3)-H Bonds with Sodium Sulfinates

A Pd(II)-catalyzed sulfonylation of unactivated C(sp3)-H bonds with sodium arylsulfinates using an 8-aminoquinoline auxiliary is described. This reaction demonstrates excellent functional group tolerance with respect to both the caboxamide starting material and the sodium arylsulfinate coupling partner, affording a broad range of aryl alkyl sulfones. Moreover, the late-stage modification of complex molecules was achieved via this sulfonylation protocol.

Ligand-promoted alkylation of C(sp3)-H and C(sp2)-H bonds

9-Methylacridine was identified as a generally effective ligand to promote a Pd(II)-catalyzed C(sp3) - H and C(sp2) - H alkylation of simple amides with various alkyl iodides. This alkylation reaction was applied to the preparation of unnatural amino acids and geometrically controlled tri- and tetrasubstituted acrylic acids.