1169983-38-3

Basic information

• Product Name: 4-(2-chloro-phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylic acid ethyl ester
• CAS NO: 1169983-38-3
• Molecular Weight: 373.879
• Mol File: 1169983-38-3.mol
• Article Data: 105

Chemical Properties

• CAS DataBase Reference: 4-(2-chloro-phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-chloro-phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylic acid ethyl ester(1169983-38-3)
• EPA Substance Registry System: 4-(2-chloro-phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylic acid ethyl ester(1169983-38-3)

Safety Data

• Hazardous Substances Data: 1169983-38-3(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 89-98-5 2-chloro-benzaldehyde 
• 126-81-8 dimedone 
• 674-82-8 4-methyleneoxetan-2-one 
• 64-17-5 ethanol 
• 873-95-0 1-amino-5,5-dimethylcyclohexen-3-one 
• 6186-89-6 ethyl methyl malonate 
• 3471-13-4 dimedone 
• 539-88-8 4-oxopentanoic acid ethyl ester 
• 626-34-6 ethyl aminocrotonate 
• 631-61-8 ammonium acetate 

Downstream Products

• 848586-30-1 2-bromomethyl-4-(2-chloro-phenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylic acid ethyl ester 

Relevant articles and documents

Aluminized polyborate-catalysed green and efficient synthesis of polyhydroquinolines under solvent-free conditions

Abstract: The present work reports a catalytic application of aluminized polyborate for the solvent-free one pot four-component green, efficient and cost-effective synthesis of polydroquinoline derivatives. The aluminized polyborate was synthesized from r

Sulfated polyborate as an eco-compatible solid acid catalyst for efficient and facile solvent-free synthesis of polyhydroquinolines

Abstract: An environmentally viable, green and efficient protocol for the synthesis of polyhydroquinolines using sulfated polyborate catalyst have been developed by Hantzsch four-component condensation between aromatic aldehydes, dimedone, ammonium acetate and ethylacetoacetate or ethylcyanoacetate at 100?°C under solvent-free condition. The sulfated polyborate catalyst is characterized by FT-IR, XRD, SEM and EDAX techniques. The noticeable features of this methodology are mild Br?nsted acidic nature of the catalyst, good to excellent product yields (85–94%), short reaction time (18–30 min), solvent-free condition, operational simplicity and applicability to a wide range of substrates (29 examples). Graphic Abstract: This work deals with sulfated polyborate catalysed green and efficient solvent-free synthesis of polyhydroquinolines.[Figure not available: see fulltext.]

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Fast and Solvent-Free Synthesis of Polyhydroquinolines Catalyzed by a Keplerate Type Giant Nanoporous Isopolyoxomolybdate as a Reusable Catalyst

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Novel magnetic nanoparticles with ionic liquid tags as a reusable catalyst in the synthesis of polyhydroquinolines

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Mo@GAA-Fe3O4MNPs: a highly efficient and environmentally friendly heterogeneous magnetic nanocatalyst for the synthesis of polyhydroquinoline derivatives

Polyhydroquinolines were efficiently obtained from a sequential four-component reaction between dimedone or 1,3-cyclohexandione, ethyl acetoacetate, or methyl acetoacetate as a β-ketoester, aldehydes, and ammonium acetate, under the catalysis of Mo@GAA-Fe3O4MNPs as a green, effective, recyclable, and environmentally friendly nanocatalyst. Due to its magnetic nature the prepared catalyst can be easily separated from the reaction mixture by an external magnet and reused several times without significant changes in catalytic activity and reaction efficiency. The catalyst was characterized using energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), vibrating sample magnetometry (VSM), scanning electron microscopy (SEM), and transmission electron microscopy (TEM).