1169983-38-3

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 626-34-6 ethyl aminocrotonate 
• 126-81-8 dimedone 
• 3471-13-4 dimedone 
• 141-97-9 ethyl acetoacetate 
• 6186-89-6 ethyl methyl malonate 
• 539-88-8 4-oxopentanoic acid ethyl ester 
• 631-61-8 ammonium acetate 
• 674-82-8 4-methyleneoxetan-2-one 
• 64-17-5 ethanol 
• 873-95-0 1-amino-5,5-dimethylcyclohexen-3-one 

Downstream Products

• 848586-30-1 2-bromomethyl-4-(2-chloro-phenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Aluminized polyborate-catalysed green and efficient synthesis of polyhydroquinolines under solvent-free conditions

Abstract: The present work reports a catalytic application of aluminized polyborate for the solvent-free one pot four-component green, efficient and cost-effective synthesis of polydroquinoline derivatives. The aluminized polyborate was synthesized from r

MgO nanoparticles as a recyclable heterogeneous catalyst for the synthesis of polyhydroquinoline derivatives under solvent free conditions

Magnesium oxide nanopartticels in average size between 35-120 nm were prepared by sonochemistry method. Synthesis of polyhydroquinoline derivatives using MgO nanoparticles from the reaction of dimedone, benzaldehyde, ethyl acetoacetate and ammonium acetat

Sulfated polyborate as an eco-compatible solid acid catalyst for efficient and facile solvent-free synthesis of polyhydroquinolines

Abstract: An environmentally viable, green and efficient protocol for the synthesis of polyhydroquinolines using sulfated polyborate catalyst have been developed by Hantzsch four-component condensation between aromatic aldehydes, dimedone, ammonium acetate and ethylacetoacetate or ethylcyanoacetate at 100?°C under solvent-free condition. The sulfated polyborate catalyst is characterized by FT-IR, XRD, SEM and EDAX techniques. The noticeable features of this methodology are mild Br?nsted acidic nature of the catalyst, good to excellent product yields (85–94%), short reaction time (18–30 min), solvent-free condition, operational simplicity and applicability to a wide range of substrates (29 examples). Graphic Abstract: This work deals with sulfated polyborate catalysed green and efficient solvent-free synthesis of polyhydroquinolines.[Figure not available: see fulltext.]

FeNH4(SO4)2·12H2O (alum)-catalyzed preparation of 1,4-dihydropyridines: Improved conditions for the Hantzsch reaction

FeNH4(SO4)2-12H2O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford 1,4-dihydropyridines. The work-up is easy, and the products are obtained

Surface modified SPIONs-Cr(VI) ions-immobilized organic-inorganic hybrid as a magnetically recyclable nanocatalyst for rapid synthesis of polyhydroquinolines under solvent-free conditions at room temperature

In this work, a magnetic hybrid dichromate nanocomposite with triphenylphosphine surface modified superparamagnetic iron oxide nanoparticles (SPIONs) as a recyclable nanocatalyst was designed, prepared and characterized by Fourier transform infrared spect

ClO4 ?/Zr-MCM-41 nanoparticles prepared at mild conditions: a novel solid acid catalyst for the synthesis of polyhydroquinolines

One-pot four-component reaction of aldehydes, dimedone, ethyl cyanoacetate or ethyl acetoacetate and ammonium acetate was studied in the presence of perchlorated Zr-MCM-41 (ClO4 ?/Zr-MCM-41) nanoparticles for the synthesis of dihydropyridines. Zr-MCM-41 nanoparticles with various molar ratios of Si/Zr were synthesized by sol–gel method under mild conditions, and then ClO4 ?/Zr-MCM-41 samples with different calcination temperatures were prepared and characterized by XRD, FT-IR and SEM techniques. The characterization results show the presence of perchlorate in the mesostructure of Zr-MCM-41 and the catalytic performance experiments show that ClO4 ?/Zr-MCM-41 with Si/Zr molar ratio of 25 and calcinations temperature of 300?°C has the best catalytic activity. The catalyst can be recovered easily and reused many times with moderate decrease in activity.

Efficient one-pot synthesis of polyhydroquinoline derivatives using silica sulfuric acid as a heterogeneous and reusable catalyst under conventional heating and energy-saving microwave irradiation

An efficient Hantzsch four-component condensation reaction for the synthesis of polyhydroquinoline derivatives was reported under two conditions: solvent-free conventional heating and energy-saving microwave irradiation. The process is simple and environm

Synthesis and characterization of magnetic bromochromate hybrid nanomaterials with triphenylphosphine surface-modified iron oxide nanoparticles and their catalytic application in multicomponent reactions

In this work, the preparation of a new magnetic hybrid core-shell nanomaterial is reported in four steps. The magnetic Fe3O4 nanoparticles were synthesized via a simple hydrothermal system. Tetraethyl orthosilicate was used as a sour

Nucleophilic, heterocyclic, carbene-catalyzed, solvent-free, one-pot synthesis of polyhydroquinolines via multicomponent hantzsch reaction: An efficient and ecofriendly approach

A simple, efficient, and ecofriendly one-pot method has been reported for the synthesis of polyhydroquinolines in excellent yield using nucleophilic heterocyclic carbene as catalyst. The generalized approach is the Hantzsch four-component reaction of arom

Nickel(II) immobilized on dithizone–boehmite nanoparticles: as a highly efficient and recyclable nanocatalyst for the synthesis of polyhydroquinolines and sulfoxidation reaction

In this work, in the first stage, boehmite nanoparticles were easily fabricated via addition of NaOH solution to a solution of Al(NO3)3.9H2O at room temperature in water. Then, nickel–dithizone catalyst was supported on bo