117039-85-7

Basic information

• Product Name: 4H-3,1-Benzoxazin-4-one, 6-methyl-2-phenyl-
• CAS NO: 117039-85-7
• Molecular Formula: C15H11NO2
• Molecular Weight: 237.258
• Mol File: 117039-85-7.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 4H-3,1-Benzoxazin-4-one, 6-methyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-3,1-Benzoxazin-4-one, 6-methyl-2-phenyl-(117039-85-7)
• EPA Substance Registry System: 4H-3,1-Benzoxazin-4-one, 6-methyl-2-phenyl-(117039-85-7)

Safety Data

• Hazardous Substances Data: 117039-85-7(Hazardous Substances Data)

Upstream product

• 15104-17-3 2-phenyl-6-methyl-1,4-dihydro-4-oxoquinoline 
• 59490-95-8 2-benzamido-5-methylbenzoic acid 
• 136634-27-0 (5-methyl-2,1-benzisoxazol-3-yl)(phenyl)methanone 
• 117039-84-6 3-chloro-6-methyl-2-phenyl-4(1H)-quinolinone 
• 13228-36-9 5-methyl-2-phenyl-1H-indole 
• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 1663-61-2 triethoxymethylbenzene 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 135754-82-4 3-methyl-N-methoxy-N-methylbenzamide 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 29289-13-2 2-iodo-4-methylaniline 
• 98-88-4 benzoyl chloride 
• 495-18-1 Benzohydroxamic acid 

Downstream Products

• 1256947-85-9 C₂₂H₁₈N₄O₂ 
• 1256947-90-6 C₂₂H₁₆N₄O 
• 52263-96-4 N-(2-benzoyl-4-methylphenyl)benzamide 
• 17852-28-7 2-amino-5-methylbenzophenone 
• 1437780-39-6 9-methyl-5-phenylindazolo[3,2-b]quinazolin-7(5H)-one 

Relevant articles and documents

Recyclable palladium-catalyzed carbonylative annulation of 2-iodoanilines with acid anhydrides: A practical synthesis of 2-alkylbenzoxazinones

A highly efficient heterogeneous palladium-catalyzed carbonylative annulation of 2-iodoanilines and acid anhydrides has been developed. The reaction proceeds effectively in toluene using N,N-diisopropylethylamine (DiPEA) as the base at 100 °C under 2 bar of CO and provides a novel, general, and practical method for the assembly of a wide variety of 2-alkylbenzoxazinones with high functional group tolerance and good to excellent yields. This supported palladium complex can be readily separated from the product and recovered by a simple filtration of the reaction solution and reused up to seven times with almost consistent catalytic efficiency.

Recyclable Heterogeneous Palladium-Catalyzed Carbonylative Cyclization of 2-Iodoanilines with Aryl Iodides Leading to 2-Arylbenzoxazinones

A highly efficient and practical heterogeneous palladium-catalyzed carbonylative coupling of 2-iodoanilines with aryl iodides has been developed. The reaction occurs smoothly in toluene at 110 °C with N, N -diisopropylethylamine as base under carbon monoxide (5 bar) and offers a general and powerful tool for the construction of various valuable 2-arylbenzoxazinones with excellent atom-economy, high functional group tolerance, good to high yields, and easy recyclability of the palladium catalyst. The reaction is the first example of heterogeneous palladium-catalyzed carbonylative coupling for the preparation of diverse 2-arylbenzoxazinones from commercially easily available 2-iodoanilines and aryl iodides.

Oxidative NHC catalysis for base-free synthesis of benzoxazinones and benzoazoles by thermal activated NHCs precursor ionic liquid catalyst using air as oxidant

A reusable thermal activated NHC precursor ionic liquid catalyst ([BMIm]2[WO4]) has been prepared and developed for the synthesis of nitrogen-containing heterocycles such as benzoxazinones and benzoazoles through imines activation. [BMIm]2[WO4] exhibited the good activity for the base-free condensation and oxidative NHC catalysis tandem under air atmosphere. The catalyst can be recovered and reused for at least five runs in gram scale synthesis without any decrease in catalytic activity. Furthermore, the control experiments demonstrated that the reaction involved formation of aromatic aldimines, NHC-catalyzed oxidative formation of imidoyl azoliums and intramolecular cyclization to generate the product.