117574-74-0Relevant articles and documents
Dual-Mode HDAC Prodrug for Covalent Modification and Subsequent Inhibitor Release
Daniel, Kevin B.,Sullivan, Eric D.,Chen, Yao,Chan, Joshua C.,Jennings, Patricia A.,Fierke, Carol A.,Cohen, Seth M.
, p. 4812 - 4821 (2015)
Histone deacetylase inhibitors (HDACi) target abnormal epigenetic states associated with a variety of pathologies, including cancer. Here, the development of a prodrug of the canonical broad-spectrum HDACi suberoylanilide hydroxamic acid (SAHA) is describ
Diels-alder trapping of ortho-quinone methides. A new entry to substituted xanthene- 1,4-diones
Giraud, Luc,Giraud, Anne
, p. 1153 - 1160 (2007/10/03)
Highly regioselective Diels-Alder reactions of a non-protected β-hydroxy quinone have been achieved after formation of chelated lithium alkoxides. In this report, we demonstrate on a model system, that the selectivity of reactions based on 1,3-dioxy-subst
SYNTHESIS OF DIQUINONE DERIVATIVES OF DEUTEROPORPHYRIN IX FOR THE STUDY OF THE FIRST STAGE IN THE PROCESS OF PHOTOSYNTHESIS
Borovkov, V. V.,Evstigneeva, R. P.,Makova, S. Z.
, p. 142 - 147 (2007/10/02)
Diquinone derivatives of deuteroporphyrin IX containing covalent bridges of different lengths between the chromophores have been synthesized.The compounds were prepared by the condensation of hydroxy-quinones with deuteroporphyrin IX using a mixed anhydri