117744-87-3

Upstream product

• 75-15-0 carbon disulfide 
• 696-62-8 para-iodoanisole 
• 109-89-7 diethylamine 
• 5720-07-0 4-methoxyphenylboronic acid 
• 148-18-5 sodium N,N-diethyldithiocarbamate 
• 97-77-8 disulfiram 
• 147-84-2 Diethyldithiocarbamic acid 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 78597-95-2 1-(butylsulfanyl)-4-methoxybenzene 
• 59693-94-6 cyclohexyl-4-methoxyphenyl sulfide 
• 26905-24-8 1-benzylsulfanyl-4-methoxy-benzene 

Relevant academic research and scientific papers

A Highly Efficient CuCl 2 -Catalyzed C-S Coupling of Aryl Iodides with Tetraalkylthiuram Disulfides: Synthesis of Aryl Dithiocarbamates

A highly efficient copper(II)-catalyzed C-S cross-coupling reaction of aryl iodides with tetraalkylthiuram disulfides was developed. With only 1 mol% of CuCl 2 as catalyst, zinc powder as reductant, and K 2 CO 3 as base, aryl iodides reacted with tetraalkylthiuram disulfides in DMSO furnishing the corresponding aryl dithiocarbamates in good to excellent yields. This protocol is an improvement of previous work, it features convenient performance, low addition of catalyst, no requirement for any ligand, and provides good yields. The method has a broad substrate scope and uses cheap and readily available starting materials.

Synthesis of Phenyl Dithiocarbamates Starting from Sodium Dialkyldithiocarbamates and Aryl Boronic Acids: a Copper Catalyzed S-Arylation

A convenient and efficient protocol for the S-arylation of sodium dialkyldithiocarbamates was developed. With the catalysis of copper(I) bromide, sodium dialkyldithiocarbamates coupled with aryl boronic acids giving the C-S coupling products smoothly in g

Copper-Catalyzed Synthesis of S-Aryl Dithiocarbamates from Tetraalkylthiuram Disulfides and Aryl Iodides in Water

An efficient approach for the copper-catalyzed synthesis of aryl dithiocarbamates from aryl iodides and tetraalkylthiuram disulfides in water is described. Without additional ligand and organic solvent, the coupling reaction could provide a series of S-aryl dithiocarbamates in moderate to good yields.

Copper-Catalyzed C(sp2)-S Coupling Reactions for the Synthesis of Aryl Dithiocarbamates with Thiuram Disulfide Reagents

An efficient protocol for the copper-catalyzed preparation of aryl dithiocarbamates from aryl iodides and inexpensive, environmentally benign tetraalkylthiuram disulfides was developed. The features of mild reaction conditions, high yields, and broad substrate scope render this new approach synthetically attractive for the preparation of potentially biologically active compounds.

A method for the synthesis of thio-carbamate

The invention belongs to the technical field of chemical synthesis and discloses a dithiocarbamate synthesis method. The dithiocarbamate synthesis method comprises that in an organic solvent, Ar-B(OH)2, NHR1R2 and carbon disulfide as raw materials and a copper salt and alkali as promoters undergo a reaction at a temperature of 60-120 DEG C for 10-24h with stirring, after the reaction, the reaction product is cooled to a room temperature, then is filtered and then is subjected to reduced pressure distillation for solvent removal so that a crude product is obtained, and the crude product is purified by column chromatography so that dithiocarbamate is obtained. The dithiocarbamate synthesis method realizes dithiocarbamate synthesis by one step, has simple and easy processes and a high product yield, utilizes cheap and easily available raw materials, has a low synthesis cost and has great industrial production values.

Copper-mediated coupling of boronic acids, amines, and carbon disulfide: An approach to organic dithiocarbamates

An efficient copper-mediated three-component coupling reaction of boronic acids, amines, and carbon disulfide has been developed, which provides a new approach to a wide range of functionalized dithiocarbamates in good to excellent yields. The present methodology has many advantages, such as mild reaction conditions, easily available substrates, wide substrate scope, and high functional-group tolerance.

A magnetically recyclable iron oxide-supported copper oxide nanocatalyst (Fe3O4-CuO) for one-pot synthesis of: S -aryl dithiocarbamates under solvent-free conditions

A green, convenient and efficient procedure is reported for the synthesis of S-aryl dithiocarbamates by a simple one-pot three component Ullmann-type condensation of an amine, carbon disulfide and an aryl iodide. Magnetically separable and reusable copper

One-pot synthesis of aryl alkyl thioethers and diaryl disulfides using carbon disulfide as a sulfur surrogate in the presence of diethylamine catalyzed by copper(I) iodide in polyethylene glycol (PEG200)

A copper catalyzed one-pot protocol for the preparation of aryl alkyl thioethers and diaryl disulfides using carbon disulfide as the sulfur source and diethylamine in polyethylene glycol (PEG200) is described.

Transition metal-free procedure for the synthesis of S-aryl dithiocarbamates using aryl diazonium fluoroborate in water at room temperature

A convenient, efficient and green procedure for the synthesis of S-aryl dithiocarbamates has been developed by a simple one-pot condensation of aryl diazonium fluoroborate, carbon disulfide and amine in the absence of any transition metal catalyst in water at room temperature. The reactions of a variety of substituted aryl diazonium fluoroborates, and cyclic and open chain amines, have been addressed. The products are purified by crystallization from ethanol and the process does not involve any hazardous solvent.