118533-24-7

Upstream product

• 108-30-5 succinic acid anhydride 
• 110522-81-1 5’-O-dimethoxytrityl-N²-phenoxyacetyl-2’-deoxyguanosine 
• 14316-61-1 phenoxyacetic anhydride 
• 961-07-9 2'-Deoxyguanosine 
• 109464-23-5 N-(9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-benzamide 
• 81144-43-6 5'-O-(p,p'-dimethoxytrityl)-2'-deoxyguanosine 

Relevant academic research and scientific papers

Synthesis of oligodeoxyribonucleoside methylphosphonates containing 2- aminopurine

Oligodeoxyribonucleoside methylphosphonates containing multiple 2- aminopurine bases were synthesized by solid-phase phosphonamidite chemistry for investigating their triple helix formation with natural DNA or other duplex targets and for cellular uptake studies of the methylphosphonate oligomers. The base-labile phenoxyacetyl group was used as the N2-amino protecting group for 2-aminopurine, allowing the final deprotection of the oligomers to be performed under the standard ehtylenediamine condition.