120106-62-9Relevant academic research and scientific papers
Synthesis of Diarylethynes from Aryldiazonium Salts by Using Calcium Carbide as an Alkyne Source in a Deep Eutectic Solvent
Ma, Xiaolong,Li, Zheng
, p. 631 - 635 (2021)
An efficient method for the synthesis of diarylethynes from aryldiazonium salts by using calcium carbide as an alkyne source at room temperature in a deep eutectic solvent is described. The salient features of this protocol are an inexpensive and easy-to-handle alkyne source, a nonvolatile and recyclable solvent, mild conditions, and a simple workup procedure.
Potassium tert -Butoxide Promoted Synthesis of 4,5-Diaryl-2 H -1,2,3-triazoles from Tosylhydrazones and Nitriles
Qiu, Shanguang,Chen, Yuxue,Song, Xinming,Liu, Li,Liu, Xi,Wu, Luyong
supporting information, p. 86 - 90 (2020/11/02)
Intermolecular cycloaddition of tosylhydrazones with nitriles was investigated. t -BuOK was shown to be an excellent base for increasing the effectiveness of the reaction in this protocol, and homocoupling of the tosylhydrazones was significantly inhibited by using xylene as a solvent. Through this transformation, a variety of 4,5-diaryl-2 H -1,2,3-triazoles were prepared in good to excellent yields and with high purities. The process is azide-free and transition-metal-free.
General Synthesis of Tri-Carbo-Substituted N2-Aryl-1,2,3-triazoles via Cu-Catalyzed Annulation of Azirines with Aryldiazonium Salts
Cheung, Chi Wai,Feng, Fang-Fang,Li, Jun-Kuan,Liu, Xuan-Yu,Ma, Jun-An,Zhang, Fa-Guang
, p. 10872 - 10883 (2020/09/23)
The general synthesis of fully substituted N2-aryl-1,2,3-triazoles is hitherto challenging compared with that of the N1-aryl counterparts. Herein, we describe a Cu-catalyzed annulation reaction of azirines and aryldiazonium salts. This regiospecific metho
Preparation method of 4-5 - diphenyl substituted triazole compound
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Paragraph 0025-0026, (2020/09/12)
The invention relates to a preparation method of a 4,5-diphenyl substituted triazole compound. The preparation method comprises the following steps: enabling a compound shown as in a formula I in thedescription and anhydrous hydrazine to react for 5-6 hou
A high-efficient preparation NH - 1, 2, 3 triazole compounds
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Paragraph 0020-0025, (2019/03/21)
The invention discloses a method for efficiently preparing NH-1,2,3 triazole compound. An alkyne compound is used for being oxidized by an oxidizing agent, NaN3 or TMSN3 serves as a nitrogen source, the oxidizing agent is one of Ph(OAc)2, KMnO4, MnO2, PhI(CF3CO2)2, Mn(OAc)3, PhIO, (NH4)2Ce(NO3)6, and reaction is performed at indoor temperature to obtain the NH-1,2,3 triazole compound. The process of synthesizing the NH-1,2,3 triazole compound from simple alkyne and particularly electric neutrality or electron-rich alkyne is achieved, in this way, synthesis of the NH-1,2,3 triazole compound is more direct and simpler, and the potential application value of the NH-1,2,3 triazole compound is achieved better.
Catalyst-Free Regioselective N2 Arylation of 1,2,3-Triazoles Using Diaryl Iodonium Salts
Roshandel, Sahar,Lunn, Maiko J.,Rasul, Golam,Muthiah Ravinson, Daniel Sylvinson,Suri, Suresh C.,Prakash, G. K. Surya
supporting information, p. 6255 - 6258 (2019/08/26)
The widespread application of 1,2,3-triazoles in pharmaceuticals has resulted in substantial interest toward developing efficient postmodification methods. Whereas there are many postmodification methods available to obtain N1-substituted 1,2,3-triazoles, developing a selective and convenient protocol to synthesize N2-aryl-1,2,3-triazoles has been challenging. We report a catalyst-free and regioselective method to access N2-aryl-1,2,3-triazoles in good to excellent yields (66-97%). This scalable postmodification protocol is effective for a wide range of substrates.
4,5-diphenyl substituted triazole compound as well as preparation method and application of 4,5-diphenyl substituted triazole compound
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Paragraph 0027-0028, (2019/04/02)
The invention relates to a 4,5-diphenyl substituted triazole compound as well as a preparation method and an application of the 4,5-diphenyl substituted triazole compound. The structure of the 4,5-diphenyl substituted triazole compound is shown in the description, wherein X is selected from O or S. The 4,5-diphenyl substituted triazole compound shows better anti-insect activity for cotton bollworms.
Method for preparing 4,5-diaryl-2H-1,2,3-triazole compound
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Paragraph 0028-0033, (2018/12/05)
The invention relates to a method for preparing a 4,5-diaryl-2H-1,2,3-triazole compound. The method specifically comprises steps as shown in the description, wherein a compound of formula II as shownin the description is reacted with R2CN to generate a co
Catalyst and solvent free microwave-assisted synthesis of substituted 1,2,3-triazoles
Roshandel, Sahar,Suri, Suresh C.,Marcischak, Jacob C.,Rasul, Golam,Surya Prakash
supporting information, p. 3700 - 3704 (2018/08/21)
We report a microwave-assisted catalyst and solvent free synthesis of 1,2,3-triazoles through the cycloaddition of trimethylsilylazide and acetylenes. Utilization of a thermally stable azide source, elimination of a metal catalyst, solvent or any additives, and a convenient isolation procedure result in an overall greener approach to access 1,2,3-triazoles on a practical scale with good to excellent yields (55-99%).
Triazole-imidazole (TA-IM) derivatives as ultrafast fluorescent probes for selective Ag+ detection
Lai, Qi,Liu, Qing,He, Ying,Zhao, Kai,Wei, Chiyu,Wojtas, Lukasz,Shi, Xiaodong,Song, Zhiguang
supporting information, p. 7801 - 7805 (2018/11/21)
1,2,3-Triazole-imidazole derivatives (TA-IM) were prepared as fluorescent probes for silver ion detection. The design principle is the incorporation of an intramolecular H-bond between the imidazole and triazole moiety that enables a co-planar conformation to achieve fluorescence emission in the UV-blue range. Screening of different metal ions revealed excellent binding affinity of this new class of compounds toward silver ions in aqueous solution. The novel probe provided ultrafast detection (30 s) even for a very low concentration of silver ions (in the nM range) with good linear correlation, making it a practical sensor for detection of silver ions.
