120706-60-7Relevant academic research and scientific papers
Effect of Stereochemistry on Chirality and Gelation Properties of Supramolecular Self-Assemblies
Qin, Minggao,Zhang, Yaqian,Xing, Chao,Yang, Li,Zhao, Changli,Dou, Xiaoqiu,Feng, Chuanliang
, p. 3119 - 3129 (2021)
Although chiral nanostructures have been fabricated at various structural levels, the transfer and amplification of chirality from molecules to supramolecular self-assemblies are still puzzling, especially for heterochiral molecules. Herein, four series o
Tunable Supramolecular Assembly and Photoswitchable Conversion of Cyclodextrin/Diphenylalanine-Based 1D and 2D Nanostructures
Sun, He-Lue,Chen, Yong,Han, Xu,Liu, Yu
, p. 7062 - 7065 (2017)
A photocontrolled, interconvertible supramolecular 2D-nanosheet/1D-nanotube system was constructed through the supramolecular assembly of adamantanyl-modified diphenylalanine with azobenzene-bridged bis(β-cyclodextrin). The nanosheet exhibited a greater f
Photo-Controllable Catalysis and Chiral Monosaccharide Recognition Induced by Cyclodextrin Derivatives
Chen, Lei,Chen, Yong,Zhang, Yi,Liu, Yu
, p. 7654 - 7658 (2021)
A supramolecular catalytic system was constructed from polycationic α-cyclodextrin (6-Iz-α-CD) and gold nanoparticles (AuNP) using a supramolecular assembly strategy. The cavity of cyclodextrin is the channel by which the substrate molecules come into con
Photo/chemo dual-controlled reversible morphological conversion and chiral modulation of supramolecular nanohelixes with nanosquares and nanofibers
Zhang, Wen,Chen, Yong,Yu, Jie,Zhang, Xu-Jie,Liu, Yu
, p. 14274 - 14277 (2016)
A photo/chemo dually interconvertible system was constructed through the supramolecular assembly of azobenzene-diphenylalanine (Azo-FF) with α-cyclodextrin. The resultant chiral nanohelix was able to interconvert into a nanosquare upon irradiation at different wavelengths, but into a nanofiber upon changing solvent polarity, which provides a feasible way to achieve highly ordered nanostructures with various morphologies, dimensions and chiralities.
PhFl polystyrene: A new resin for solid phase organic synthesis
Bleicher, Konrad H.,Wareing, James R.
, p. 4587 - 4590 (1998)
A 9-phenylfluoren-9-yl polystyrene based resin is described for the attachment of nitrogen and oxygen nucleophiles. Higher acid stability compared to standard trityl resins makes this solid support an interesting alternative in solid phase organic synthes
Soft structure formation and cancer cell transport mechanisms of a folic acid-dipeptide conjugate
Kaur, Gagandeep,Shukla, Akansha,Sivakumar, Sri,Verma, Sandeep
, p. 248 - 255 (2015)
Folic acid (FA) is a low-molecular-weight micronutrient, which plays a critical role in the prevention of birth defects and cancers. It is also essential for biochemical pathways responsible for DNA synthesis and maintenance and for the generation of new red blood cells. Cellular trafficking of FA and folate is based on its high-affinity binding to cognate folate receptor, a protein commonly expressed in several human cancers. Thus, folate conjugates of drugs, plasmids, biosensors, contrast, and radiodiagnostic imaging agents have been used for assisted delivery in folate receptor-positive cancer cells, via endocytosis pathways. This report describes morphologies of soft structures from a fully characterized FA-dipeptide conjugate and detailed mechanistic studies of its cancer cell uptake, as tracked by the inherent fluorescence of the conjugate.
A self-assembled tetrapeptide that acts as a “turn-on” fluorescent sensor for Hg2+ ion
Tomar, Kalpana,Kaur, Gagandeep,Verma, Sandeep,Ramanathan, Gurunath
, p. 3653 - 3656 (2018)
The tetrapeptide (Bz-ΔPhe(p-NPh2)-L-DOPA(protected)-L-Phe-L-Phe-OMe was designed to incorporate seven phenyl rings so that it's conformation, self-assembly and application in Hg2+ ions sensing could be studied. Peptide molecules adopted an overlapping β-turn of type III/III conformation in crystals. The peptide showed a highly selective turn-on response towards mercuric ion over other metal ions with a 10-fold enhancement in fluorescence intensity. This intensity change coupled with the selectivity of the peptide towards mercury allowed us to demonstrate simple colorimetric dip sensing of Hg2+ ions. The technique provides a highly selective and effective way to detect Hg2+ ions. The peptide also self-assembled into nanospheres with diameter ranges from 100 to 500 nm. Mercuric ion coordination enabled these peptide nanospheres to aggregate into well-defined nanoparticles. The enhanced fluorescence upon Hg2+ addition demonstrates that peptide scaffolds can be exploited in the development of different selective sensors.
Ribozymomimetic chemical synthesis of peptide bond using phosphorous acid/oxirane mediators
Bayryamov,Danalev,Vassilev
, p. 338 - 344 (2011)
Chemical Equation Presented A model system is created that mimics natural ribosome as well as the way of ribozyme action. It uses oxirane analogue as condensation reagent and H3PO3 as activator for the carboxyl group and as protecting reagent for the NH2
Tunable Nanosupramolecular Aggregates Mediated by Host–Guest Complexation
Zhang, Wen,Zhang, Ying -Ming,Li, Sheng -Hua,Cui, Yong -Liang,Yu, Jie,Liu, Yu
, p. 11452 - 11456 (2016)
Nanosupramolecular assemblies with controlled topological features have inventive applications in fundamental studies and material manufacturing. Herein, a variety of morphologically interesting aggregates have been constructed using the supramolecular modulation with bipyridinium-modified diphenylalanine derivative (BP-FF). Benefiting from the high binding affinity of bipyridinium group with four different macrocyclic receptors, namely cucurbit[7]uril, cucurbit[8]uril, pillar[5]arene, and tetrasulfonated crown ether, we have succeeded in tuning the topological aggregates of BP-FF from fine nanofibers to nanorods, octahedron-like nanostructure, helical nanowires, and rectangular nanosheets without any tedious chemical modification. This supramolecular approach may provide us a powerful method to construct well-defined nanostructures with different morphologies that can be conveniently controlled by facile host–guest interactions.
Hydrogen-bonding interactions in ferrocene-peptide conjugates containing valine
Beheshti, Samaneh,Lataifeh, Anas,Kraatz, Heinz-Bernhard
, p. 1117 - 1125 (2011)
The synthesis and characterization of a series of ferrocene (Fc) peptide conjugates containing the amino acid valine is reported, where the peptide substituents are part of the hydrophobic sequence of the amyloid β-peptide. The hydrogen-bonding (H-bonding
