61123-13-5 Usage
Uses
Used in Pharmaceutical Industry:
PYR-PHE-PHE-GLY-LEU-MET-NH2 is used as a therapeutic agent for its potential roles in protein structure, function, and signaling processes in biological systems. The peptide may have applications in the development of drugs targeting specific proteins or pathways involved in diseases.
Used in Nutritional Supplements:
PYR-PHE-PHE-GLY-LEU-MET-NH2 is used as a nutritional supplement to provide essential amino acids for protein synthesis and support various metabolic processes in the body.
Used in Cosmetics Industry:
PYR-PHE-PHE-GLY-LEU-MET-NH2 is used as an ingredient in cosmetic products for its potential role in promoting skin health and regeneration due to the presence of essential amino acids.
Used in Research and Development:
PYR-PHE-PHE-GLY-LEU-MET-NH2 is used as a research tool to study the structure, function, and signaling processes of proteins in biological systems, which can contribute to the development of new therapies and treatments for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 61123-13-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,1,2 and 3 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 61123-13:
(7*6)+(6*1)+(5*1)+(4*2)+(3*3)+(2*1)+(1*3)=75
75 % 10 = 5
So 61123-13-5 is a valid CAS Registry Number.
InChI:InChI=1/C36H49N7O7S/c1-22(2)18-27(35(49)41-25(32(37)46)16-17-51-3)40-31(45)21-38-33(47)28(19-23-10-6-4-7-11-23)42-36(50)29(20-24-12-8-5-9-13-24)43-34(48)26-14-15-30(44)39-26/h4-13,22,25-29H,14-21H2,1-3H3,(H2,37,46)(H,38,47)(H,39,44)(H,40,45)(H,41,49)(H,42,50)(H,43,48)/t25-,26-,27-,28-,29-/m0/s1
61123-13-5Relevant articles and documents
SYNTHESIS OF 6-11 SUBSTANCE P FRAGMENT ANALOGS CONTAINING ENANTIOMERS OF NATURALLY OCCURRING AMINO ACIDS
Janecka, Anna,Koziolkiewicz, Wiktor,Wasiak, Tadeusz
, p. 761 - 765 (2007/10/02)
Seven analogs of 6-11 Substance P fragment in which one or more naturally occurring amino acids were replaced by their enantiomers were synthesized.Three of them: 6, D-Phe8, His9>SP(6-11), 6, D-Phe8, D-Leu10>SP(6-11) and 6, D-Phe8, D-Leu10>SP(6-11) are shown to be 6>SP(6-11) antagonists.If applied 30 sec before 6>SP(6-11) they reduce the contraction of isolated rat jejunum caused by that hexapeptide.
Catalytic Transfer Hydrogenation in Synthesis of Substance P
Sivanandaiah, K. M.,Rangaraju, N. S.
, p. 787 - 792 (2007/10/02)
The utility of catalytic transfer hydrogenation (CTH) in the synthesis of longer peptides has been demonstrated by the stepwise synthesis of Substance P in the solution phase.The technique of CTH using formic acid as a hydrogen donor provides a facile method for the removal of protecting groups such as benzyloxycarbonyl and nitro in the synthesis of medium-sized peptides also.Except in the case of glutaminyl peptides where the purity and yield are affected to some extent by cyclization, the products are generally pure requiring minimum purification and the yields are good.
SYNTHESIS OF HEXAPEPTIDES FRAGMENT OF SUBSTANCE P AND ITS PYROGLUTAMYL-ANALOG
Lipkowski, Andrzej W.,Majewski, Tadeusz,Drabarek, Stefania
, p. 1707 - 1712 (2007/10/02)
Syntheses of Substance P, C-terminal hexapeptide fragment (Gln-Phe-Phe-Gly-Leu-Met-NH2), and its pyroglutamyl-analog which is formed as a by-product on decoupling step in synthesis of C-terminal hexapeptide fragment of substance P are described.
