122709-21-1

Basic information

• Product Name: (S)-3-BOC-4-(METHOXYMETHYLCARBAMOYL)-2,2-DIMETHYLOXAZOLIDINE
• Synonyms: (S)-3-BOC-4-(METHOXYMETHYLCARBAMOYL)-2,2-DIMETHYLOXAZOLIDINE;tert-butyl 4-[Methoxy(Methyl)carbaMoyl]-2,2-diMethyl-1,3-oxazolidine-3-carboxylate;(S)-4-(Methoxy-Methyl-carbaMoyl)-2,2-diMethyl-oxazolidine-3-carboxylic acid tert-butyl ester;(S)-tert-Butyl 4-(Methoxy(Methyl)carbaMoyl)-2,2-diMethyloxazolidine-3-carboxylate;tert-Butyl (S)-4-(methoxy(methyl)carbamoyl)-2,2-dimethyloxazolidine-3-carboxylate;(4S)-3-Oxazolidinecarboxylic acid, 4-[(methoxymethylamino)carbonyl]-2,2-dimethyl-, 1,1-dimethylethyl ester
• CAS NO: 122709-21-1
• Molecular Formula: C₁₃H₂₄N₂O₅
• Molecular Weight: 288.34
• Mol File: 122709-21-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 349.7°Cat760mmHg
• Flash Point: 165.3°C
• Appearance: /
• Density: 1.118g/cm³
• Vapor Pressure: 4.63E-05mmHg at 25°C
• Refractive Index: 1.473
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-3-BOC-4-(METHOXYMETHYLCARBAMOYL)-2,2-DIMETHYLOXAZOLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-BOC-4-(METHOXYMETHYLCARBAMOYL)-2,2-DIMETHYLOXAZOLIDINE(122709-21-1)
• EPA Substance Registry System: (S)-3-BOC-4-(METHOXYMETHYLCARBAMOYL)-2,2-DIMETHYLOXAZOLIDINE(122709-21-1)

Safety Data

• Hazardous Substances Data: 122709-21-1(Hazardous Substances Data)

Usage

General Description

(S)-3-BOC-4-(methoxymethylcarbamoyl)-2,2-dimethyloxazolidine is a chemical compound with a complex structure. It contains a BOC (tert-butyloxycarbonyl) protecting group on the nitrogen atom, a methoxymethylcarbamoyl group, and a 2,2-dimethyloxazolidine ring system. (S)-3-BOC-4-(METHOXYMETHYLCARBAMOYL)-2,2-DIMETHYLOXAZOLIDINE is commonly used as a reagent in organic synthesis and medicinal chemistry. Its unique structure and properties make it useful for protecting and modifying functional groups in various chemical reactions, as well as for the synthesis of pharmaceutical compounds and other bioactive molecules. The compound's specific properties and applications make it valuable in the field of chemical research and drug discovery.

InChI:InChI=1/C13H24N2O5/c1-12(2,3)20-11(17)15-9(8-19-13(15,4)5)10(16)14(6)18-7/h9H,8H2,1-7H3/t9-/m0/s1

Upstream product

• 122709-20-0 N-(tert-butoxycarbonyl)-L-serine N'-methoxy-N'-methylamide 
• 77-76-9 2,2-dimethoxy-propane 
• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 3262-72-4 (R)-N-tert-butoxycarbonyl serine 
• 59524-02-6 N-tert-butoxycarbonyl-L-serine benzyl ester 
• 67-64-1 acetone 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 25952-53-8 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride 
• 139009-66-8 (S)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidine-4-carboxylic acid 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 785828-28-6 tert-butyl (4S)-4-acetyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 
• 175696-50-1 tert-butyl [(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]carbamate 
• 162107-48-4 tert-butyl (R)-4-ethynyl-2,2-dimethyloxazolidine-3-carboxylate 
• 336625-43-5 (2S,3R)-2-(tert-butoxycarbonylamino)-1,3-dibenzyloxyoctadecane-6-one 
• 336625-42-4 (2S,3R)-3-benzyloxy-2-(tert-butoxycarbonylamino)-1-hydroxyoctadecane-6-one 
• 336625-41-3 tert-butyl (4S,1'R)-4-(1'-benzyloxy-4'-oxohexadecyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 336625-40-2 tert-butyl (4S,1'R)-4-(1'-benzyloxy-4'-hydroxyhexadecyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 336625-45-7 (S)-4-((R)-1-Benzyloxy-4,5-dihydroxy-pentyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 336625-39-9 tert-butyl (4S,1'R)-4-(1'-benzyloxy-4'-pentenyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 149180-94-9 tert-butyl (4S,1'R)-4-(1'-benzyloxy-4'-oxobutyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 488835-85-4 (4S)-4-(4-benzyloxyphenyl)-3-tert-butoxycarbonyl-2,2-dimethyloxazolidine 
• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Direct Synthesis of N -Protected Serine- And Threonine-Derived Weinreb Amides via Diboronic Acid Anhydride-Catalyzed Dehydrative Amidation: Application to the Concise Synthesis of -Garner's Aldehyde

An efficient method for the direct synthesis of Weinreb amides derived from serine and threonine derivatives via diboronic acid anhydride-catalyzed hydroxy-directed amidation is described. This is the first successful example of the synthesis of serine- or threonine-derived Weinreb amides using catalytic dehydrative amidations. The methodology could be applied to the concise synthesis of Garner's aldehyde.

Novel Easily Recyclable Bifunctional Phosphonic Acid Carrying Tripeptides for the Stereoselective Michael Addition of Aldehydes with Nitroalkenes

A novel bifunctional organocatalyst library combining both aminocatalysis and phosphonic acid activation was used for the first time as an efficient tool for the stereoselective Michael addition of aldehydes with several aromatic nitroalkenes with good selectivities up to 95:5 dr and 93:7 er. Due to their high water solubility, the catalysts were easily recyclable and could be reused over several cycles without any significant loss of selectivity.

Protein and peptide-free synthetic vaccines against streptococcus pneumoniae type 3

The present invention provides a protein- and peptide-free conjugate comprising a synthetic carbohydrate and a carrier molecule, wherein the synthetic carbohydrate is a Streptococcus pneumoniae type 3 capsular polysaccharide related carbohydrate and the carrier molecule is a glycosphingolipid. Said conjugate and pharmaceutical composition thereof are useful for immunization against diseases associated with Streptococcus pneumoniae, and more specifically against diseases associated with Streptococcus pneumoniae type 3.