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1227210-31-2

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1227210-31-2 Usage

General Description

1-(2-bromoethyl)-5-(bromomethyl)-3-nitro-1H-pyrazole is a chemical compound with the molecular formula C6H6Br2N4O2. It is a pyrazole derivative with two bromine atoms and a nitro group attached to the pyrazole ring. 1-(2-bromoethyl)-5-(bromomethyl)-3-nitro-1H-pyrazole is commonly used in organic synthesis and pharmaceutical research as a building block for the preparation of various biologically active molecules. Its structural features make it a valuable intermediate for the synthesis of advanced materials, fine chemicals, and pharmaceuticals. It has potential applications in medicinal chemistry and agrochemicals due to its unique biological activities. Additionally, it can be used as a starting material for the synthesis of new pyrazole derivatives with potential therapeutic properties.

Check Digit Verification of cas no

The CAS Registry Mumber 1227210-31-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,2,1 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1227210-31:
(9*1)+(8*2)+(7*2)+(6*7)+(5*2)+(4*1)+(3*0)+(2*3)+(1*1)=102
102 % 10 = 2
So 1227210-31-2 is a valid CAS Registry Number.

1227210-31-2Relevant articles and documents

BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY

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Paragraph 0414-0415, (2021/05/15)

The present invention relates to compounds of formula (I) useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

NOVEL COMPOUNDS

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, (2016/04/20)

The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase L1 (UCHL1). The invention further relates to the use of DUB inhibitors in the treatment of cancer and other indications. Compounds of the invention include compounds having the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 to R8 are as defined herein.

SUBSTITUTED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

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, (2015/03/13)

The present disclosure relates to pyrimidine compounds of formula (I), their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to process of preparation of these pyrimidine compounds, and to pharmaceutical compositions containing them. The compounds of the present disclosure are useful in the treatment, prevention or suppression of diseases and disorders mediated by epidermal growth factor receptor (EGFR) family kinases.

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