124-64-1 Usage
Chemical Properties
Clear light pink or yellow-green solution
Uses
Different sources of media describe the Uses of 124-64-1 differently. You can refer to the following data:
1. Flame-retarding agent for cotton fabrics. May
be used in combination with triethylolamine and
urea (Roxel process) or with triethanolamine and
tris(1-aziridinyl) phosphine oxide.
2. Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H2O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl4.3H2O). It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications.
Definition
A crystalline compound made by the reaction of
phosphine, formaldehyde, and hydrochloric acid.
General Description
Clear slightly viscous,colorless to yellow liquid (20% H2O solution).
Air & Water Reactions
Hygroscopic. Water soluble.
Reactivity Profile
Tetrakis(hydroxymethyl)phosphonium chloride reacts vigorously with oxidizers and alkalis. Reacts with cellulose.
Health Hazard
ACUTE/CHRONIC HAZARDS: Tetrakis(hydroxymethyl)phosphonium chloride may be corrosive. When heated to decomposition, it may emit very toxic fumes of POx, hydrogen chloride and bis(chloromethyl)ether. Decomposition of Tetrakis(hydroxymethyl)phosphonium chloride in an aqueous environment may produce phosphine, formaldehyde and hydrogen chloride.
Fire Hazard
Tetrakis(hydroxymethyl)phosphonium chloride is probably combustible.
Flammability and Explosibility
Nonflammable
Purification Methods
Crystallise it from AcOH and dry it at 100o in a vacuum. An 80% w/v aqueous solution has d4 1.33 [Reeves J Am Chem Soc 77 3923 1955]. [Beilstein 1 IV 3062.]
Check Digit Verification of cas no
The CAS Registry Mumber 124-64-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 124-64:
(5*1)+(4*2)+(3*4)+(2*6)+(1*4)=41
41 % 10 = 1
So 124-64-1 is a valid CAS Registry Number.
InChI:InChI=1/2C4H12O4P.C2H2O4/c2*5-1-9(2-6,3-7)4-8;3-1(4)2(5)6/h2*5-8H,1-4H2;(H,3,4)(H,5,6)/q2*+1;/p-2
124-64-1Relevant articles and documents
Hoffman, A.
, p. 1684 - 1688 (1921)
Synthesis of monophosphines directly from white phosphorus
Scott, Daniel J.,Cammarata, Jose,Schimpf, Maximilian,Wolf, Robert
, p. 458 - 464 (2021/04/09)
Monophosphorus compounds are of enormous industrial importance due to the crucial roles they play in applications such as pharmaceuticals, photoinitiators and ligands for catalysis, among many others. White phosphorus (P4) is the key starting material for the preparation of all such chemicals. However, current production depends on indirect and inefficient, multi-step procedures. Here, we report a simple, effective ‘one-pot’ synthesis of a wide range of organic and inorganic monophosphorus species directly from P4. Reduction of P4 using tri-n-butyltin hydride and subsequent treatment with various electrophiles affords compounds that are of key importance for the chemical industry, and it requires only mild conditions and inexpensive, easily handled reagents. Crucially, we also demonstrate facile and efficient recycling and ultimately catalytic use of the tributyltin reagent, thereby avoiding the formation of substantial Sn-containing waste. Accessible, industrially relevant products include the fumigant PH3, the reducing agent hypophosphorous acid and the flame-retardant precursor tetrakis(hydroxymethyl)phosphonium chloride. [Figure not available: see fulltext.]
