1245641-48-8

Basic information

• Product Name: (1S,4aS)-Methyl 6-Methoxy-1,4a-diMethyl-9-oxo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate
• Synonyms: 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-6-methoxy-1,4a-dimethyl-9-oxo-, methyl ester, (1R,4aR)-rel-
• CAS NO: 1245641-48-8
• Molecular Formula: C19H24O4
• Molecular Weight: 316.39146
• Mol File: 1245641-48-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1S,4aS)-Methyl 6-Methoxy-1,4a-diMethyl-9-oxo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,4aS)-Methyl 6-Methoxy-1,4a-diMethyl-9-oxo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate(1245641-48-8)
• EPA Substance Registry System: (1S,4aS)-Methyl 6-Methoxy-1,4a-diMethyl-9-oxo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate(1245641-48-8)

Safety Data

• Hazardous Substances Data: 1245641-48-8(Hazardous Substances Data)

Usage

General Description

The chemical "(1S,4aS)-methyl 6-methoxy-1,4a-dimethyl-9-oxo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate" is a methyl ester derivative of 1,4a-dimethyl-9-oxo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid. It is a complex organic compound containing a phenanthrene core and a carboxylate functional group. The presence of a methoxy group and two methyl groups on the phenanthrene core adds to its structural complexity. This chemical may have potential applications in pharmaceuticals, organic synthesis, or other industrial uses due to its intricate structure and functional groups.

Upstream product

• 292638-85-8 acrylic acid methyl ester 
• 107-13-1 acrylonitrile 
• 1231-74-9 methyl 12-methoxypodocarpa-8,11,13-trien-19-oate 
• 1231-74-9 methyl O-methylpodocarpate 
• 74-85-1 ethene 
• 1045-54-1 6α-Brom-7-oxo-O-methylpodocarpsaeure-methylester 
• 4614-56-6 methyl podocarpate 
• 5947-49-9 podocarpic acid 
• 501-65-5 diphenyl acetylene 
• 623-43-8 methyl crotonate 
• 107-02-8 acrolein 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 33169-07-2 (1S,4aS,10aR)-1,4a-Dimethyl-6-oxo-1,2,3,4,4a,6,7,8,10,10a-decahydro-phenanthrene-1-carboxylic acid 
• 23526-52-5 methyl 12-methoxypodocarpa-6,8,11,13-tetraen-19-oate 
• 23526-53-6 methyl 7β-hydroxy-12-methoxypodocarpa-8,11,13-trien-19-oate 
• 64597-67-7 (1S,2R,3S)-3-(2-Hydroxy-5-methoxy-phenyl)-2-methoxycarbonylmethyl-1,3-dimethyl-cyclohexanecarboxylic acid methyl ester 
• 1865-97-0 methyl O-methyl-Δ^5,6-7-ketopodocarpate 
• 1045-54-1 6α-Brom-7-oxo-O-methylpodocarpsaeure-methylester 

Relevant articles and documents

Phenolic diterpenoid derivatives as anti-influenza a virus agents

A series of diterpenoid derivatives based on podocarpic acid were synthesized and evaluated as anti-influenza A virus agents. Several of the novel podocarpic acid derivatives exhibited nanomolar activities against an H1N1 influenza A virus (A/Puerto Rico/8/34) that was resistant to two anti-influenza drugs, oseltamivir and amantadine. This class of compounds inhibits the influenza virus by targeting the viral hemagglutinin-mediated membrane fusion. These results indicated that podocarpic acid derivatives may serve as potential drug candidates to fight drug-resistant influenza A virus infections.

Skeletal rearrangements of ring C aromatic diterpenoids

The structure of a naphthalene derivative obtained by rearrangement of 13-methoxytotara-5,8,11,13-tetraen-7α-ol (2) has been revised to 5-(5′-isopropyl-6′-methoxy-2′-methyl-1′-naphthyl)-2- methylpent-2-ene (7). A minor oxidation product of 13-methoxytotar

Reactions of η2-tetracarbonylmanganese complexes derived from podocarpic acid with electrophiles; functionalization of ring C

Reaction of tetracarbonylmanganese(I) complexes derived from podocarpic acid (1) with electrophilic bromine or iodine in CCl4 leads to 14-halogenated derivatives inaccessible by direct halogenation.Similar reactions in protic solvents lead to the formation of γ-lactones in high yield.The structure of one of these was established unequivocally by X-ray crystallograohy.Attempted oxidation of the C-Mn bond with a number of reagents proved generally to be unsuccessful.