124607-18-7

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 99-93-4 4-Hydroxyacetophenone 
• 54696-05-8 4'-benzyloxy-acetophenone 
• 78589-65-8 3-(4-hydroxyphenyl)prop-2-yn-1-oic acid 
• 2979-06-8 ethyl (E)-4-hydroxycinnamate 
• 7400-08-0 p-Coumaric Acid 
• 77103-47-0 ethyl (4-hydroxybenzoyl)acetate 
• 53090-45-2 ethyl 3-[4-(benzyloxy)phenyl]-3-oxopropanoate 
• 2999-40-8 1,3,5-triacetoxybenzene 

Downstream Products

• 74512-60-0 5,7-dimethoxy-4-(4-methoxyphenyl)-2H-1-benzopyran-2-one 
• 88126-44-7 5,7-dimethoxy-4-(4-hydroxyphenyl)-2H-1-benzopyran-2-one 

Relevant academic research and scientific papers

Synthesis of New Naturally Occuring 4-Phenyl-2H-1-benzopyran-2-ones

5,7-Dimethoxy-4-(4-hydroxyphenyl)-2H-1-benzopyran-2-one and 5,7-dimethoxy-4-(4-methoxyphenyl)-2H-1-benzopyran-2-one, two new neoflavonoids occuring in Courtarea hexandra have been synthesized via Pechmann condensation.Attempts made to synthesize another 4-arylcoumarin, 5-hydroxy-7-methoxy-4-(2,5-dihydroxyphenyl)-2H-1-benzopyran-2-one, constituent of the same plant, led to the formation of the hitherto unknown 2-ethoxy-6-hydroxy-4H-1-benzopyran-4-one.

An efficient synthesis of neoflavonoid antioxidants based on Montmorillonite K-10 catalysis

A new approach to synthesis of neoflavonoids, based on a high yielding Montmorillonite K-10 catalyzed lactone ring forming cyclization process, is described. The utility of this methodology is exemplified by its employment in the preparation of the substituted 4-phenylneoflavonoids 1-8. The free radical scavenging properties of these substances were evaluated. The neoflavonoids 1 and 5, which mimic esculetin-type antioxidants, were observed to quench hydrazyl free radicals.

Flavonoids Syntheses. VI. Synthesis and Spectral Properties of 4-Arylcoumarins (Neoflavones)

Eight neoflavones were synthesized for examination of their spectral properties.In the mass spectra, 2'-oxygenated neoflavones showed characteristic fragments owing to dehydrxylation or demethoxylation.Other spectral data ultraviolet, proton and carbon-13 nuclear magnetic resonance, however, showed no specific features that could be used to characterize the structures.Keywords--neoflavone synthesis; 4-arylcoumarin; 2'-oxygenated neoflavone; mass spectrum

SYNTHESIS OF 4-ARYLCOUMARINS FROM COUTAREA HEXANDRA

Key Word Index - Coutarea hexandra; Rubiaceae; neoflavonoids; 4-arylcoumarins; synthesis. - The structures assigned to the 5,7-dimethoxy-4-arylcoumarins isolated from Coutarea hexandra have been confirmed by synthesis, via Pechmann condensation of phlorog