74512-60-0

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 5,7-dimethoxy-4-(4-methoxyphenyl)-
• CAS NO: 74512-60-0
• Molecular Formula: C18H16O5
• Molecular Weight: 312.322
• Mol File: 74512-60-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 5,7-dimethoxy-4-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 5,7-dimethoxy-4-(4-methoxyphenyl)-(74512-60-0)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 5,7-dimethoxy-4-(4-methoxyphenyl)-(74512-60-0)

Safety Data

• Hazardous Substances Data: 74512-60-0(Hazardous Substances Data)

Upstream product

• 33397-21-6 tris(4-methoxyphenyl)bismuth 
• 5720-07-0 4-methoxyphenylboronic acid 
• 185418-17-1 5,7-dimethoxy-4-trifluoromethylsulfonyloxychromen-2-one 
• 97746-14-0 2-Hydroxy-4,6,4'-trimethoxybenzophenone 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 97746-16-2 5,7-dihydroxy-4-(4-methoxyphenyl)-2H-1-benzopyran-2-one 
• 77-78-1 dimethyl sulfate 
• 186581-53-3 diazomethane 
• 130236-65-6 7,4'-dihydroxy-5-methoxy-4-phenylcoumarin 
• 124607-18-7 5,7-dihydroxy-4-(4-hydroxyphenyl)-2H-1-benzopyran-2-one 
• 500-99-2 3,5-dimethoxyphenol 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 108-73-6 3,5-dihydroxyphenol 
• 621-23-8 1,2,3-trimethoxybenzene 

Downstream Products

• 1415387-96-0 1-(cis-3,5-dimethylpiperidin-1-yl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)propan-1-one 

Relevant articles and documents

Pd-catalyzed chemo-selective mono-arylations and bis-arylations of functionalized 4-chlorocoumarins with triarylbismuths as threefold arylating reagents

Cross-coupling reactions of differently substituted 4-chlorocoumarins were studied under palladium catalysis using triarylbismuths as threefold arylating reagents. The high reactivity of 4-chlorocoumarins was demonstrated delivering mono- and bis-arylation products in a chemo-selective manner. The reaction conditions employed are simple, robust and the threefold coupling reactivity of triarylbismuth reagents was witnessed with good to high yields in 2-4 h conditions. The utility of the methodology was explored in the synthesis of a few natural occurring neoflavones (3.27-3.30). In addition, the 4-arylcoumarin 3.1 product is a useful precursor for the preparation of (R)-tolterodine.

Antioxidant and antitumor activities of 4-arylcoumarins and 4-aryl-3,4-dihydrocoumarins

Five 4-arylcoumarins (1c-g) and twelve 3,4-dihydro-4-arylcoumarins (2a-l) were synthesized and tested for antioxidant activity, antitumor activity, toxicity and structure-activity relationships analysis. 4-Arylcoumarins and 3,4-dihydro-4-arylcoumarins tha

Efficient synthesis and biological evaluation of 4-arylcoumarin derivatives

Two bioactive natural 4-arylcoumarins, 5,7,4′-trimethoxy-4- phenylcoumarin (1a), 5,7-dimethoxy-4-phenylcoumarin (1b) and five closely related derivatives 1c-g were synthesized. In vitro evaluation with a catechol subunit for antioxidant and antimicrobial activity, these compounds using standard methods showed that compounds 1d, 1f displayed promise radical scavenging activity and 1f was found to be the most active one against Bacillus dysenteriae.