1246431-52-6

Upstream product

• 409366-27-4 (3,5-dichloro-4-hydroxyphenyl)acetic acid methyl ester 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 67-56-1 methanol 

Downstream Products

• 1246431-54-8 C₁₈H₁₅Cl₃O₆ 
• 42583-41-5 2-{4-[5-(carboxymethyl)-2-methoxyphenoxy]phenyl}acetic acid 
• 59654-05-6 (+)-O-methylthalibrine 
• 14400-96-5 (S)-armepavine 
• 524-20-9 armepavine 
• 3423-02-7 (R)-(-)-O-methylarmepavine 
• 5701-00-8 (R)-O-methylarmepavine 
• 1246431-55-9 C₁₇H₁₃Cl₃O₆ 
• 5884-67-3 armepavine 
• 1934-93-6 6,7-dimethoxy-1-(4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Sequential paired electrosynthesis of a diaryl ether derivative using an electrochemical microreactor

A paired electrosynthetic conversion of a phenol to a diaryl ether derivative by using an electrochemical microreactor has been demonstrated. Sequential anodic CO coupling reaction of phenol 1 to dienone aryl ether 2 and following reduction of 2 took place to give diaryl ether derivative 3 selectively by simply passing an electrolytic solution through the electrochemical microreactor.

Synthesis of (+)-O-methylthalibrine by employing a stereocontrolled Bischler-Napieralski reaction and an electrochemically generated diaryl ether

An efficient electrochemical four-step route was developed for the preparation of diaryl ether derivatives by using halogenation and dehalogenation processes in addition to electrochemical phenolic oxidation and reduction reactions. The synthesis of (+)-O

Electrochemical construction of the diaryl ethers: A synthetic approach to o-methylthalibrine

Electrochemical dimerization of halogenated p-hydroxyphenylacetic acid derivatives followed by Zn reduction provided the corresponding diaryl ethers. Manipulation of the reduction step using several procedures increased its efficiency, which enabled the construction of o-methylthalibrine, an isoquinoline-class alkaloid.