125231-24-5

Upstream product

• 536-74-3 phenylacetylene 
• 106-40-1 4-bromo-aniline 
• 26456-05-3 10-methylacridinium perchlorate 
• 98-86-2 acetophenone 
• 98-81-7 1-bromovinylbenzene 
• 100-42-5 styrene 
• 20102-12-9 2-hydroxy-2-phenylpropionitrile 
• 81512-11-0 2-(N-4-bromophenylamino)-2-phenylpropanenitrile 

Downstream Products

• 913830-00-9 (R)-N-(4-bromophenyl)-1-phenylethylamine 
• 330793-63-0 (+)-N-(4-bromophenyl )-1-phenylethylamine 
• 330793-63-0 (-)-N-(4-bromophenyl )-1-phenylethylamine 
• 1075181-22-4 N-4-bromophenyl-N-[(1-phenyl)ethyl]amine 
• 330793-63-0 (+)-N-(4-bromophenyl)-1-phenylethylamine 
• 330793-63-0 (-)-N-(4-bromophenyl)-1-phenylethylamine 
• 898825-98-4 6-bromo-2-phenyl-quinoxaline 
• 330793-63-0 N‐(1‐phenylethyl)‐4‐bromoaniline 

Relevant academic research and scientific papers

A Au(I)-Precatalyst with a Cyclopropenium Counterion: An Unusual Ion Pair

The synthesis and X-ray crystal structure of a novel Au(I)-precatalyst applied to intermolecular alkyne hydroamination is reported. Density functional theory (DFT) calculations revealed the cyclopropenium counterion of this Au(I)-precatalyst imparts stabi

A highly regioselective Cu-exchanged tungstophosphoric acid catalyst for hydroarylation and hydroamination of alkynes

An efficient and reusable Cu-exchanged tungstophosphoric acid catalyst is demonstrated for the solvent free hydroarylation and hydroamination reactions of alkynes with numerous arene and amine derivatives, respectively. The catalyst exhibited exceptionally high activity and regioselectivity in both the reactions.

Syntheses of Triangular Gold Complexes and Their Applications in Hydroamination Reaction

Triangular all-metal complexes have aroused our research interest due to their unique structural and properties. Herein, through the facile reduction of μ3-oxo complex [μ3-O(PPh3Au)3]+BF4s

Synthesis and application of axially chiral biscarbolines with functional N-O and sulfone for 1,2-transfer hydrogenations of ketimines

A series of axially chiral biscarboline-based sulfones were synthesized from L-tryptophane and applied for enantioselective 1,2-transfer hydrogenations of ketimines using trichlorosilane. The catalyst 4e, which had a tertiary butyl group, exhibited a good conversion and high enantioselectivities up to 96%ee in the series of reactions.

Manganese-Catalyzed C?H Annulation of Ketimines with Allenes: Stereoselective Synthesis of 1-Aminoindanes

A manganese-catalyzed C?H annulation of ketimines with poly-substituted ester-activated allenes toward the synthesis of 1-aminoindanes bearing two vicinal all-substituted carbon stereocenters and an exocyclic double bond was developed. The reaction featur

Transition-Metal-Free Addition of Acetylenes to Ketimines: the First Base-Catalyzed Ethynylation of the C=N Bond

A one-pot transition metal-free synthesis of propargylamines in good to excellent yield from ketone-derived imines and aryl- and hetarylacetylenes in the presence of KOBut/DMSO superbase system (40 °C, 10 min) has been developed. The reaction i

Thiolate-Protected Au 25 (SC 2 H 4 Ph) 18 Nanoclusters as a Catalyst for Intermolecular Hydroamination of Terminal Alkynes

Au 25 (SC 2 H 4 Ph) 18 nanoclusters have high catalytic activity for hydroamination of terminal alkynes. This reaction proceeds under O 2 or air. The presence of molecular oxygen has a profound effect

Neutral and cationic cyclic (alkyl)(amino)carbene mercury [cAAC-Hg(ii)] complexes: Scope of hydroamination of alkynes with organomercury compounds

This study demonstrates the first synthesis of cyclic (alkyl)(amino)carbene (cAAC) adducts of Hg(ii), [cAACMe·HgBr(μ-Br)]2 (1a) and [cAACcy·HgBr(μ-Br)]2 (1b). Adduct 1b catalyzes intermolecular hydroamination of

An efficient proline-based homogeneous organocatalyst with recyclability

In this work, a homogeneous organocatalyst was developed for the asymmetric reduction of imines. This catalyst could be separated by cyclodextrin-modified Fe3O4@SiO2 magnetic nanoparticles and then released back into a fre

Palladium-catalyzed aerobic oxidative hydroamination of vinylarenes using anilines: A wacker-type amination pathway

A palladium-catalyzed intermolecular hydroamination of vinylarene derivatives using anilines has been developed for the first time under aerobic conditions, where the regioselective formation of N-arylketimines is accomplished. The current aerobic oxidative hydroamination pathway of anilines is distinct from that of palladiumcatalyzed hydroamination reactions that proceed to give sec-arylethylamine and arylethylamine derivatives, identifying a longstanding missing reaction pathway, Wacker-type amination, to N-arylketimines using anilines. The ready availability of both starting materials, vinylarenes and anilines, offers an attractive and facile synthetic route to N-arylketimines in good to excellent yields.