126456-65-3

Basic information

• Product Name: ethyl 3-(2,6,6-trimethyl-2-cyclohexenyl)-2-propenoate
• Synonyms: ethyl 3-(2,6,6-trimethyl-2-cyclohexenyl)-2-propenoate
• CAS NO: 126456-65-3
• Molecular Weight: 222.327
• Mol File: 126456-65-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 3-(2,6,6-trimethyl-2-cyclohexenyl)-2-propenoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(2,6,6-trimethyl-2-cyclohexenyl)-2-propenoate(126456-65-3)
• EPA Substance Registry System: ethyl 3-(2,6,6-trimethyl-2-cyclohexenyl)-2-propenoate(126456-65-3)

Safety Data

• Hazardous Substances Data: 126456-65-3(Hazardous Substances Data)

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 14505-74-9 α-cyclocitral 
• 18049-09-7 ethyl (2E,4E)-5,9-dimethyldeca-2,4,8-trienoate 
• 37384-69-3 3-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-propenoic acid 
• 64-17-5 ethanol 
• 432-25-7 2,6,6-trimethylcyclohex-1-enecarbaldehyde 
• 141-27-5 3,7-dimethyl-2,6-octadienal 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 51768-75-3 (E)-3-(2,6,6-trimethylcyclohex-2-enyl)prop-2-en-1-ol 
• 37384-69-3 3-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-propenoic acid 
• 14393-45-4 (E)-3-(2,6,6-trimethylcyclohex-1-enyl)acrylic acid 
• 176324-36-0 3-(2,6,6-Trimethyl-cyclohex-2-enyl)-selenopropionic acid Se-methyl ester 
• 124070-95-7 (1RS,7aSR)-1-(3-furyl)-4,4,7a-trimethyl-1,4,5,6,7,7a-hexahydro-2H-inden-2-one 
• 52567-52-9 3-(2,6,6-trimethyl-2-cyclohexenyl)-propanoic acid 
• 176324-37-1 3-(2,6,6-trimethyl-2-cyclohexenyl)propanal 
• 108878-63-3 3-(2,6,6-trimethyl-2-cyclohexenyl)propanol 
• 51768-83-3 3-(2',6',6'-trimethylcyclohex-2'-en-1'-yl)prop-2-enal 
• 7779-30-8 (S,E)-1-(2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-one 
• 7779-30-8 (R,E)-1-(2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-one 
• 945760-13-4 (R,E)-1-((S)-2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-ol 
• 945760-05-4 (S,E)-1-((R)-2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-ol 
• 945760-14-5 (R,E)-1-((S)-2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-yl acetate 

Relevant articles and documents

Lewis Acid-Catalyzed Intramolecular [2 + 2] Cycloaddition of α-Ester-Substituted Conjugated Dienyl- And Trienylphosphonates. New Synthesis of Functionalized Cyclic Terpenoids

α-Ester-substituted 1,3-dienylphosphonates 7 and 8, prepared by the Knoevenagel condensation, underwent intramolecular [2 + 2] cycloaddition in the presence of Lewis acid to form bicyclo[4.2.0] (26-57% yield) and bicyclo[3.2.0]skeleton (14-38% yield), respectively. Similar treatment of homologous 1,3-dienylphosphonate 11 and 1,3,5-trienylphosphonate 12 resulted in the formation of ionone derivatives (30-94% yield). The intramolecular cycloaddition reaction was applicable to several conjugated dienes bearing an ester group.

ANTINEOPLASTIC AND CURCUMIN DERIVATIVES AND METHODS OF PREPARATION AND USE

This invention comprises antineoplastic curcumin derivatives and methods of preparation and use thereof. Note is made of the acylation product of the lithium enolate of β-ionone using the acid chloride, 2(E)-3-(2,6,6-trimethycyclohex-1-en-1-yl)propenoyl chloride derived from β-cyclocitral. Particular reference is made to the isomeric compound, 1-(2,6,6-trimethylcyclohex-2-en-1-yl)-7-(2,6,6-trimethylcyclohex-1-en-1-yl)- 1,6-heptadiene-3,5-dione.

Model insect antifeedants. Synthesis of azadiradione fragments through acyl radicals cyclizations and stannane coupling reactions

A diastereoselective and versatile synthesis of the model insect antifeedant 16 related to azadiradione has been achieved in nine steps starting from α-cyclocitral 1. The key steps involve intramolecular alkene addition of an acyl radical and a Stille coupling reaction of a vinyl iodide with a stannylfuran.