126456-65-3

Upstream product

• 14505-74-9 α-cyclocitral 
• 105-36-2 ethyl bromoacetate 
• 18049-09-7 ethyl (2E,4E)-5,9-dimethyldeca-2,4,8-trienoate 
• 37384-69-3 3-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-propenoic acid 
• 64-17-5 ethanol 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 432-25-7 2,6,6-trimethylcyclohex-1-enecarbaldehyde 
• 141-27-5 3,7-dimethyl-2,6-octadienal 

Downstream Products

• 176324-34-8 ethyl 3-(2,6,6-trimethyl-2-cyclohexenyl)-propanoate 
• 51768-75-3 (E)-3-(2,6,6-trimethylcyclohex-2-enyl)prop-2-en-1-ol 
• 108878-63-3 3-(2,6,6-trimethyl-2-cyclohexenyl)propanol 
• 176324-37-1 3-(2,6,6-trimethyl-2-cyclohexenyl)propanal 
• 37384-69-3 3-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-propenoic acid 
• 14393-45-4 (E)-3-(2,6,6-trimethylcyclohex-1-enyl)acrylic acid 
• 176324-36-0 3-(2,6,6-Trimethyl-cyclohex-2-enyl)-selenopropionic acid Se-methyl ester 
• 124070-95-7 (1RS,7aSR)-1-(3-furyl)-4,4,7a-trimethyl-1,4,5,6,7,7a-hexahydro-2H-inden-2-one 
• 52567-52-9 3-(2,6,6-trimethyl-2-cyclohexenyl)-propanoic acid 
• 51768-83-3 3-(2',6',6'-trimethylcyclohex-2'-en-1'-yl)prop-2-enal 
• 7779-30-8 (S,E)-1-(2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-one 
• 7779-30-8 (R,E)-1-(2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-one 
• 945760-13-4 (R,E)-1-((S)-2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-ol 
• 945760-05-4 (S,E)-1-((R)-2,6,6-trimethylcyclohex-2-enyl)pent-1-en-3-ol 

Relevant academic research and scientific papers

Lewis Acid-Catalyzed Intramolecular [2 + 2] Cycloaddition of α-Ester-Substituted Conjugated Dienyl- And Trienylphosphonates. New Synthesis of Functionalized Cyclic Terpenoids

α-Ester-substituted 1,3-dienylphosphonates 7 and 8, prepared by the Knoevenagel condensation, underwent intramolecular [2 + 2] cycloaddition in the presence of Lewis acid to form bicyclo[4.2.0] (26-57% yield) and bicyclo[3.2.0]skeleton (14-38% yield), respectively. Similar treatment of homologous 1,3-dienylphosphonate 11 and 1,3,5-trienylphosphonate 12 resulted in the formation of ionone derivatives (30-94% yield). The intramolecular cycloaddition reaction was applicable to several conjugated dienes bearing an ester group.

ANTINEOPLASTIC AND CURCUMIN DERIVATIVES AND METHODS OF PREPARATION AND USE

This invention comprises antineoplastic curcumin derivatives and methods of preparation and use thereof. Note is made of the acylation product of the lithium enolate of β-ionone using the acid chloride, 2(E)-3-(2,6,6-trimethycyclohex-1-en-1-yl)propenoyl chloride derived from β-cyclocitral. Particular reference is made to the isomeric compound, 1-(2,6,6-trimethylcyclohex-2-en-1-yl)-7-(2,6,6-trimethylcyclohex-1-en-1-yl)- 1,6-heptadiene-3,5-dione.

The enantiomers of Iralia: preparation and odour evaluation

The enantiomers of methyl ionones 1 and 2 were prepared by an enzyme-catalysed approach. Their odour properties were evaluated by skilful perfumers.

Model insect antifeedants. Synthesis of azadiradione fragments through acyl radicals cyclizations and stannane coupling reactions

A diastereoselective and versatile synthesis of the model insect antifeedant 16 related to azadiradione has been achieved in nine steps starting from α-cyclocitral 1. The key steps involve intramolecular alkene addition of an acyl radical and a Stille coupling reaction of a vinyl iodide with a stannylfuran.

Synthesis of a CDE fragment of the insect antifeedant 12-hydroxyazadiradione

A diastereoselective and versatile synthesis of the model insect antifeedant 23 related to 12-hydroxyazadiradione has been achieved in 11 steps starting from α-cyclocitral, 1. The key steps involve intramolecular 1,3-dipolar cycloaddition of a nitrile oxide and a Stille coupling reaction of a vinyl iodide with a stannylfuran.

REFORMATSKY REACTION USING Zn/Ag COUPLE

The Reformatsky reaction is easy to run in ethereal solvents in the presence of Zn/Ag couple.From methyl γ-bromocrotonate and krtones, remified esters are fromed in refluxing Et2O, linear ones in refluxing THF.