1267498-46-3 Usage
Uses
Used in Pharmaceutical Research:
(R)-methyl 7-((2-aminoethyl)amino)-14-cyclohexyl-7,8-dihydro-6H-benzo[2,3][1,5]oxazocino[5,4-a]indole-11-carboxylate is used as a potential candidate in pharmaceutical research for its structural complexity and the possibility of biological activities. Its unique arrangement of functional groups and chiral centers may allow it to interact with various enzymes, receptors, or other biomolecules, making it a valuable compound for the development of new drugs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R)-methyl 7-((2-aminoethyl)amino)-14-cyclohexyl-7,8-dihydro-6H-benzo[2,3][1,5]oxazocino[5,4-a]indole-11-carboxylate is used as a starting point for the design and synthesis of new therapeutic agents. Its structural features can be exploited to create molecules with specific biological targets, potentially leading to the development of novel treatments for various diseases and conditions.
Used in Drug Design and Development:
(R)-methyl 7-((2-aminoethyl)amino)-14-cyclohexyl-7,8-dihydro-6H-benzo[2,3][1,5]oxazocino[5,4-a]indole-11-carboxylate is used as a structural template in drug design and development. Its unique combination of functional groups and stereochemistry can be leveraged to create new molecules with improved pharmacological properties, such as increased potency, selectivity, and bioavailability.
Used in Chemical Synthesis:
In the chemical synthesis industry, (R)-methyl 7-((2-aminoethyl)amino)-14-cyclohexyl-7,8-dihydro-6H-benzo[2,3][1,5]oxazocino[5,4-a]indole-11-carboxylate can be used as a building block or intermediate for the synthesis of more complex molecules. Its versatile structure allows for further functionalization and modification, enabling the creation of a wide range of chemical products with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1267498-46-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,7,4,9 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1267498-46:
(9*1)+(8*2)+(7*6)+(6*7)+(5*4)+(4*9)+(3*8)+(2*4)+(1*6)=203
203 % 10 = 3
So 1267498-46-3 is a valid CAS Registry Number.
1267498-46-3Relevant academic research and scientific papers
Mitsunobu inversion of a secondary alcohol with diphenylphosphoryl azide. application to the enantioselective multikilogram synthesis of a HCV polymerase inhibitor
Scott, Jeremy P.,Alam, Mahbub,Bremeyer, Nadine,Goodyear, Adrian,Wilson, Robert D.,Lam, Thientu,Zhou, George
, p. 1116 - 1123 (2012/01/03)
The development of a practical synthesis of the hepatitis C virus polymerase inhibitor 1 was necessary to support preclinical safety and human clinical studies. Significant challenges face the process chemist in developing a route to 1 that is amenable to
Discovery of (7 R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6 H -indolo[1,2- e ][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase
Narjes, Frank,Crescenzi, Benedetta,Ferrara, Marco,Habermann, J?rg,Colarusso, Stefania,Del Rosario Rico Ferreira, Maria,Stansfield, Ian,MacKay, Angela Claire,Conte, Immacolata,Ercolani, Caterina,Zaramella, Simone,Palumbi, Maria-Cecilia,Meuleman, Philip,Leroux-Roels, Geert,Giuliano, Claudio,Fiore, Fabrizio,Di Marco, Stefania,Baiocco, Paola,Koch, Uwe,Migliaccio, Giovanni,Altamura, Sergio,Laufer, Ralph,De Francesco, Raffaele,Rowley, Michael
, p. 289 - 301 (2011/03/22)
Infections caused by hepatitis C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The polymerase of HCV is responsible for the replication of viral genome and has been a prime target for drug discovery eff
