886041-66-3

Basic information

• Product Name: methyl (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)-amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate
• Synonyms: methyl (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)-amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate
• CAS NO: 886041-66-3
• Molecular Weight: 489.658
• Mol File: 886041-66-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)-amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)-amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate(886041-66-3)
• EPA Substance Registry System: methyl (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)-amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate(886041-66-3)

Safety Data

• Hazardous Substances Data: 886041-66-3(Hazardous Substances Data)

Upstream product

• 886041-55-0 methyl 14-cyclohexyl-7-oxo-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate 
• 886041-54-9 methyl (7S)-14-cyclohexyl-7-hydroxy-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate 
• 886041-53-8 3-cyclohexyl-2-{2-[(2S)-oxiran-2-ylmethoxy]phenyl}-1H-indole-6-carboxylic acid methyl ester 
• 50-00-0 formaldehyd 
• 863578-50-1 3-cyclohexyl-2-(2-hydroxy-phenyl)-1H-indole-6-carboxylic acid methyl ester 
• 1267498-46-3 methyl (7R)-7-[(2-aminoethyl)amino]-14-cyclohexyl-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate 
• 886041-65-2 methyl (7R)-7-({2-[(tert-butoxycarbonyl)amino]ethyl}amino)-14-cyclohexyl-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylate 

Downstream Products

• 1267498-35-0 C₇H₈O₃S*C₂₉H₃₇N₃O₃ 

Relevant articles and documents

Mitsunobu inversion of a secondary alcohol with diphenylphosphoryl azide. application to the enantioselective multikilogram synthesis of a HCV polymerase inhibitor

The development of a practical synthesis of the hepatitis C virus polymerase inhibitor 1 was necessary to support preclinical safety and human clinical studies. Significant challenges face the process chemist in developing a route to 1 that is amenable to

Development of a scalable chiral synthesis of MK-3281, an inhibitor of the hepatitis C virus NS5B polymerase

The development of a scalable chiral synthesis for the HCV NS5B inhibitor MK-3281 is being reported. Several alternative routes were explored and are being described. Georg Thieme Verlag Stuttgart ? New York.