127208-47-3

Upstream product

• 127208-45-1 4,5-epoxy-1-phenyl-9-decene 
• 127208-60-0 4-phenyl-1-cyclohexyl-1-butanol 
• 67281-38-3 1-(cyclohex-1-en-1-yl)-4-phenylbutan-1-one 
• 300-57-2 allylbenzene 
• 4845-04-9 1-cyclohexene-1-methanol 
• 1192-88-7 1-cyclohexene-1-carboxaldehyde 
• 637-59-2 1-Bromo-3-phenylpropane 
• 18328-11-5 3-benzyl propionaldehyde 
• 127208-57-5 10-phenyl-cis-1,6-decadiene 
• 2695-47-8 6-Bromo-1-hexene 
• 2043-61-0 cyclohexanecarbaldehyde 
• 18496-54-3 phenylbutyric acid chloride 
• 110-83-8 cyclohexene 
• 201230-82-2 carbon monoxide 

Relevant academic research and scientific papers

From Alkyl Halides to Ketones: Nickel-Catalyzed Reductive Carbonylation Utilizing Ethyl Chloroformate as the Carbonyl Source

Ketones are an important class of molecules in synthetic and medicinal chemistry. Rapid and modular synthesis of ketones remains in high demand. Described here is a nickel-catalyzed three-component reductive carbonylation method for the synthesis of dialkyl ketones. A wide range of both symmetric and asymmetric dialkyl ketones can be accessed from alkyl halides and a safe CO source, ethyl chloroformate. The approach offers complementary substrate scope to existing carbonylation methods while avoiding the use of either toxic CO or metal carbonyl reagents.

Synthesis of aliphatic ketones from allylic alcohols through consecutive isomerization and chelation-assisted hydroacylation by a rhodium catalyst

Abstract: An allylic alcohol, utilized as a precursor for an aliphatic aldehyde, reacted with olefins to afford aliphatic ketones in the presence of RhCl(PPh3)3, 2-amino-4-picoline, aniline, and benzoic acid through a tandem reaction of an isomerization and a chelation-assisted hydroacylation.