128800-36-2

Usage

Uses

Used in Pharmaceutical Industry:
Benzoic acid, 2-chloro-4,5-difluoro-, methyl ester is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, Benzoic acid, 2-chloro-4,5-difluoro-, methyl ester is utilized as a precursor in the production of agrochemicals, potentially enhancing crop protection and yield through targeted pest control.
Used in Fine Chemicals Synthesis:
Benzoic acid, 2-chloro-4,5-difluoro-, methyl ester is employed as a key building block in the synthesis of fine chemicals, contributing to the creation of specialty compounds for various applications, including fragrances, dyes, and other high-value products.
It is important to handle Benzoic acid, 2-chloro-4,5-difluoro-, methyl ester with caution due to its potential harmful effects if ingested, inhaled, or comes into contact with the skin. Proper safety measures and protective equipment are essential when working with Benzoic acid, 2-chloro-4,5-difluoro-, methyl ester.

InChI:InChI=1/C8H5ClF2O2/c1-13-8(12)4-2-6(10)7(11)3-5(4)9/h2-3H,1H3

Upstream product

• 110877-64-0 2-chloro-4,5-difluorobenzoic acid 
• 75-36-5 acetyl chloride 
• 67-56-1 methanol 
• 60-29-7 diethyl ether 
• 74-88-4 methyl iodide 
• 124-41-4 sodium methylate 
• 121872-95-5 2-chloro-4,5-difluorobenzoyl chloride 

Downstream Products

• 1012869-96-3 2-Chloro-4-dimethylamino-5-fluoro-benzoic acid methyl ester 
• 1246388-86-2 tert-Butyl 4-((5-chloro-2-fluoro-4-(methoxycarbonyl)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate 

Relevant academic research and scientific papers

THIADIAZOLE MODULATORS OF S1P AND METHODS OF MAKING AND USING

The invention is directed to compounds of the formula: wherein each of the variables are defined herein, as well as methods of making and using the compounds as agonists of S1P1 and/or S1P5 for instance treating an autoimmune disease.

Modulators of S1P and Methods of Making And Using

The invention is directed to Compounds of Formula I: as well as methods of making and using the compounds.

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

COMPOUNDS AND METHODS FOR 18F LABELED AGENTS

The present invention relates to novel compounds suitable for or already radiolabeled with 18F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled compounds are characterized by Formula II, wherein the substituents G, Q, L, Y and U have the meaning as defined in the specification and claims.

Compounds and methods for F labelled agents

This invention relates to novel compounds suitable for or already radiolabeled with 18F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled compounds are characterized by Formula 11, wherein the subs

PROCESSES FOR THE PREPARATION OF PYRAZOLO[1,5-a]-1,3,5-TRIAZINES AND INTERMEDIATES THEREOF

The present invention provides novel processes and intermediates for preparing corticotropin releasing factor (CRF) receptor antagonists having the structure below which are useful in treating CRF-related disorders such as anxiety and depression.

Compounds useful as reversible inhibitors of cysteine proteases

Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formula (Ia) and (Ib) where R2, R3, R4, R5, R6, R7, R8, Het and X are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds.

Compounds useful as reversible inhibitors of cysteine proteases

Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (I), (II), (Ia) and (Ib) further defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds.

Novel compounds useful as reversible inhibitors of cysteine proteases

Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formula (Ia) and (Ib) where R2, R3, R4, R5, R6, R7, R8, Het and X are defined herein. The co

Nucleus-fluorinated aromatic carboxylates and processes for their production

A process for producing nucleus-fluorinated aromatic carboxylates, which comprise nucleus-fluorinating aromatic carboxylates of the following formula (1) with a fluorinating agent to obtain nucleus-fluorinated aromatic carboxylates of the following formula (2): STR1 wherein R1 is an alkyl group, an aryl group or a fluoroalkyl group, each of A and B is at least one member selected from the group consisting of a hydrogen atom, a halogen atom, an alkyl group, an aryl group and a fluoroalkyl group, and n and m are integers satisfying m+n=6, provided that m is 1 or 2, provided that at least one A is an activated chlorine or bromine atom, and B corresponding to such an activated chlorine or bromine atom is a fluorine atom.