129137-16-2

Upstream product

• 98-86-2 acetophenone 
• 119900-89-9 Methyl (S)-4-phosphono-3-(tert-butyldiphenylsiloxy)butyrate 
• 129122-36-7 2-(4-Fluoro-benzoyl)-4-methyl-3-(2-oxo-2-phenyl-ethyl)-pentanoic acid ethyl ester 
• 129122-69-6 3-(2,2-Dibromoethenyl)-2-(4-fluorophenyl)-4-(1-methylethyl)-6-phenylpyridine 
• 129122-70-9 3-Ethynyl-2-(4-fluorophenyl)-4-(1-methylethyl)-6-phenylpyridine 
• 129122-38-9 2-(4-fluorophenyl)-4-(1-methylethyl)-6-phenyl-3-pyridinecarboxaldehyde 
• 119900-72-0 (S)-4--3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>butanoic acid methyl ester 
• 119899-86-4 (S)-4-(Methoxychlorophosphinyl)-3-[[(t-butyl)diphenylsilyl]oxy]-butanoic acid, methyl ester 
• 119899-81-9 (S)-4-(hydroxymethoxyphosphinyl)-3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>butanoic acid methyl ester 
• 119673-71-1 Methyl 3S-((t-butyl)diphenylsilyloxy)-4-bromo butanoate 
• 119673-72-2 (S)-4-iodo-3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>butanoic acid methyl ester 
• 88759-56-2 (S)-bromo-3-hydroxybutyric acid methyl ester 
• 122253-01-4 2-(4-fluorophenyl)-4-(1-methylethyl)-6-phenyl-3-pyridinemethanol 
• 36597-08-7 (E)-4-methyl-1-phenyl-2-penten-1-one 

Downstream Products

• 129122-02-7 (S)-4-[[[2-(4-Fluorophenyl)-4-(1-methylethyl)-6-phenyl-3-pyridinyl]ethynyl]hydroxyphosphinyl]-3-hydroxybutanoic acid, dilithium salt 

Relevant academic research and scientific papers

Phosphorus-Containing Inhibitors of HMG-CoA Reductase. 2. Synthesis and Biological Activites of a Series of Substituted Pyrydynes Containing a Hydroxyphosphinyl Moiety

A series of 2,3,4,(5),6-substituted pyridines containing a hydroxyphosphinyl functionality have been prepared and were evaluated for their ability to inhibit the enzyme HMG-CoA reductase.Systematic substitution of both R1-R4 and X-Y