Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1294504-68-9

Post Buying Request

1294504-68-9 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • CyclopropanecarboxaMide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-1-[(2R)-2-hydroxy-3-(phenylMethoxy)propyl]-1H-indol-5-yl]-

    Cas No: 1294504-68-9

  • No Data

  • No Data

  • No Data

  • Hangzhou Huarong Pharm Co., Ltd.
  • Contact Supplier
  • CyclopropanecarboxaMide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-1-[(2R)-2-hydroxy-3-(phenylMethoxy)propyl]-1H-indol-5-yl]-

    Cas No: 1294504-68-9

  • No Data

  • No Data

  • No Data

  • Hangzhou Dingyan Chem Co., Ltd
  • Contact Supplier
  • CyclopropanecarboxaMide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-1-[(2R)-2-hydroxy-3-(phenylMethoxy)propyl]-1H-indol-5-yl]-

    Cas No: 1294504-68-9

  • No Data

  • No Data

  • No Data

  • ZHEJIANG JIUZHOU CHEM CO.,LTD
  • Contact Supplier
  • CyclopropanecarboxaMide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-1-[(2R)-2-hydroxy-3-(phenylMethoxy)propyl]-1H-indol-5-yl]-

    Cas No: 1294504-68-9

  • No Data

  • No Data

  • No Data

  • GZ HONESTCHEM CO., LTD
  • Contact Supplier

1294504-68-9 Usage

General Description

The chemical "Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[2-[1,1-dimethyl-2-(phenylmethoxy)ethyl]-6-fluoro-1-[(2R)-2-hydroxy-3-(phenylmethoxy)propyl]-1H-indol-5-yl]-" is a complex compound consisting of a cyclopropanecarboxamide backbone with several substituents. It contains a difluoro-benzodioxol ring, a dimethyl-phenylmethoxyethyl group, a fluoro-hydroxy-phenylmethoxypropyl group, and an indolyl ring. CyclopropanecarboxaMide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[2-[1,1-diMethyl-2-(phenylMethoxy)ethyl]-6-fluoro-1-[(2R)-2-hydroxy-3-(phenylMethoxy)propyl]-1H-indol-5-yl]- is likely to have specific biological activities and could be used potentially for pharmacological purposes. The combination of different functional groups in this chemical suggests that it may have diverse interactions with biological systems and could be useful for further research and development in the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 1294504-68-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,9,4,5,0 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1294504-68:
(9*1)+(8*2)+(7*9)+(6*4)+(5*5)+(4*0)+(3*4)+(2*6)+(1*8)=169
169 % 10 = 9
So 1294504-68-9 is a valid CAS Registry Number.

1294504-68-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-N-(1-(3-(benzyloxy)-2-hydroxypropyl)-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-5-yl)-1-(2,2-difluorohenzo[d][1,3] dioxol-5-yl)cyclopropanecarboxamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1294504-68-9 SDS

1294504-68-9Relevant articles and documents

Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases

-

, (2021/04/21)

The present invention features compositions comprising a plurality of therapeutic agents wherein the presence of one therapeutic agent enhances the properties of at least one other therapeutic agent. In one embodiment, the therapeutic agents are cystic fibrosis transmembrane conductance regulators (CFTR) such as a CFTR corrector or CFTR potentiator for the treatment of CFTR mediated diseases such as cystic fibrosis. Methods and kits thereof are also disclosed.

Tezacaftor intermediate II preparation method

-

Paragraph 0042, (2019/11/20)

The invention provides a Tezacaftor intermediate II preparation method, which comprises: carrying out a reaction on a compound represented by a formula I and used as a reaction raw material under theactions of a catalyst and an alkali in an organic solvent to obtain a Tezacaftor intermediate II, wherein the reaction equation is defined in the specification, and the catalyst of the reaction is a mixture of a copper salt and N-methylpyrrolidone. According to the present invention, by using the completely-new CuI/NMP catalytic system, the problem that the Pd reagent is used in the prior art is eliminated so as to greatly reduce the production cost, the influence of the residual metal palladium on the drug Tezacaftor can be avoided, and importantly the reaction yield of the key step for Tezacaftor intermediate II synthesis is significantly increased by using the completely-new CuI/NMP catalytic system so as to greatly increase the Tezacaftor intermediate II production efficiency and further reduce the production cost.

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

-

, (2015/09/22)

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1294504-68-9